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TranscriptomicsGenome-wide DNA methylation analysis of seminoma-like TCam-2 cells during transition into an embryonal carcinoma-like state
Illumina 450k DNA methylation microarray analysis of seminoma-like TCam-2 cells xenografted in nude mice. 2120EP embryonal carcinoma cells served as control. TCam-2 cells acquire pluripotency and become epigenetically reprogrammed to an embryonal carcinoma-like state during in vivo growth. This anal...
ORGANISM(S): Homo sapiens 
2015-08-01 | E-GEOD-60787 | biostudies-arrayexpress
TranscriptomicsGenome-wide cDNA expression analysis of seminoma-like TCam-2 cells during transition into an embryonal carcinoma-like state
Illumina cDNA expression microarray analysis of seminoma-like TCam-2 cells xenografted in nude mice. 2120EP embryonal carcinoma cells served as control. TCam-2 cells acquire pluripotency and become epigenetically reprogrammed to an embryonal carcinoma-like state during in vivo growth. This analysis ...
ORGANISM(S): Homo sapiens 
2015-08-01 | E-GEOD-60698 | biostudies-arrayexpress
GenomicsChIP-seq. analysis of pan-histone 3 acetylation in Romidepsin treated TCam-2
ChIP-seq. analysis of TCam-2 16 h after 10 nanomolar Romidepsin application. DMSO treated cells were used as controls. For ChIP, an antibody against histone H3 pan-acetylation was used. These data are part of the article 'The Histone Deacetylase Inhibitor Romidepsin Efficiently Targets Cisplatin-res...
ORGANISM(S): Homo sapiens 
2016-09-01 | E-GEOD-78262 | biostudies-arrayexpress
UnknownNANOG promoter methylation and expression correlation during normal and malignant human germ cell development.
Not available
S-EPMC3052918 | biostudies-literature
TranscriptomicsTranscription factor TFAP2C regulates major programs required for murine fetal germ cell maintenance and haploinsufficiency predisposes to teratomas in male mice
Maintenance and maturation of primordial germ cells is controlled by complex genetic and epigenetic cascades, and disturbances in this network lead to either infertility or malignant aberration. Transcription factor Tcfap2c / TFAP2C has been described to be essential for primordial germ cell mainten...
ORGANISM(S): Mus musculus 
2014-01-30 | E-GEOD-45941 | biostudies-arrayexpress
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