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ProteomicsCross-linking mass spectrometry analysis of trimeric complex of CRM1, SNP1 and RanGTP cross-linked with BS3
An X-ray crystallography structure of the trimeric nuclear export complex of CRM1, SNP1 and RanGTP is available on the PDB database with the ID 3GJX. To get an XL-MS dataset of a clean sample of a stable protein complex for benchmarking purposes, another sample from the protein expression, purificat...
ORGANISM(S): Escherichia coli 
2020-10-20 | PXD014359 | Pride
Technical dataset 
ProteomicsReanalysis of Cross-Linking Mass Spectrometry data from a ribisomal cellular fraction for benchmarking purposes
Reanalysis of a cross-linked ribosomal cellular fraction dataset, that is a subset of a fragmentation parameters optimization dataset (PRIDE project PXD006131). The HCD fragmented part of the dataset was searched with the Cross-Linking MS identification tools OpenPepXL, pLink2, Kojak and XiSearch.
ORGANISM(S): Homo sapiens (Human) 
2020-10-20 | PXD014520 | Pride
Technical dataset Cross-linking Bs3 
ProteomicsReanalysis of a synthetic cross-linked peptide library with OpenPepXL for benchmarking purposes
Reanalysis of a synthetic crosslinked peptide library dataset. The three replicates of the XL-MS experiment with the non-cleavable cross-linker DSS from the dataset published in Beveridge et al., Nature Commun., 2020 (PRIDE project PXD014337) were searched with the XL-MS identification tool OpenPepX...
ORGANISM(S): Streptococcus pyogenes ABC020006030 
2020-10-20 | PXD021417 | Pride
Technical dataset 
ProteomicsComparison of OpenPepXL and xQuest on a Labeled Cross-Linking MS dataset
These data sets are part of a large study aimed at the comparison of experimental and computational workflows used in chemical cross-linking coupled to mass spectrometry. Bovine serum albumin (BSA) was used as a model protein. Two different cross-linking chemistries were used: disuccinimidyl suberat...
ORGANISM(S): Bos taurus (Bovine) 
2020-10-20 | PXD014523 | Pride
Chemical cross-linking  dss  pdh  dmtmm  structural proteomics  bovine serum albumin 
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