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Proteomicsproteotoxic stress response in in-vitro 2 human neuronal models 3
We used an untargeted pro-24 teomic approach using liquid chromatography-tandem mass spectrometry (LC-MS/MS) to identify 25 and characterize time-series proteome-wide changes in dose-responsive mild and extreme proteo-26 toxic stress models in medulloblastoma [Daoy], neuroblastoma [SH-SY5Y] and diff...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD051826 | Pride
Neurons  proteostasis  heat shock  proteotoxic stress  stress response  proteomics 
ProteomicsProteomic dynamics in response to iron deficiency and hypoxia
Iron and oxygen deficiencies are common features in pathophysiological conditions such as is-chemia, neurological diseases, and cancer. Cellular adaptive responses to such deficiencies include repression of mitochondrial respiration as well as promotion of angiogenesis and cell cycle con-trol. We ap...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-17 | PXD030380 | Pride
Oxygen sensing Hippocampus Hypoxia Neu-ronal cells Iron deficiency Transcriptome analysis Quantitative proteomics 
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