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Effects of elicited and pre-existing purified anti-Neu5Gc antibodies on human endothelial cells
Human beings are unable to synthetize the glycolylated neuraminidic acid (Neu5Gc) following a mutation of the CMAH gene and diet induced anti-Neu5Gc antibodies develop in the first year of life. However, because humans can absorb Neu5Gc which deposits at low levels on endothelial cells (EC), activat...
ORGANISM(S): Homo sapiens 
2019-07-18 | GSE117146 | GEO
Neu5Gc intake increases the expression of colorectal cancer-related genes in the APCMin+ mouse
Clinical cohort data suggest that high consumption of red meat containing N-glycolylneuraminic acid (Neu5Gc) may increase colorectal prevalence, therefore, we investigated the effect of high Neu5Gc intake on colon cancer using the APCMin/+ mouse model . Ten APCMin/+ male mice were divided into two g...
ORGANISM(S): Mus musculus 
2023-11-30 | GSE218116 | GEO
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