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UnknownNGS-Based S. aureus Typing and Outbreak Analysis in Clinical Microbiology Laboratories: Lessons Learned From a Swiss-Wide Proficiency Test.
Not available
S-EPMC7793906 | biostudies-literature
ProteomicsA Chemical Disruptor of the ClpX Chaperone Complex Attenuates Multiresistant Staphylococcus aureus Virulence
The Staphylococcus aureus ClpXP protease is an important regulator of cell homeostasis and virulence. Here we utilize a high-throughput screen against the ClpXP complex and identify a specific inhibitor of the ClpX chaperone that disrupts its oligomeric state. Synthesis of 34 derivatives revealed th...
ORGANISM(S): Staphylococcus aureus 
2017-09-14 | PXD007259 | Pride
Proteomics Staphylococcus aureus Proteolysis High-throughput screening Antivirulence 
UnknownMeta-analysis of two studies in the presence of heterogeneity with applications in rare diseases.
Not available
S-EPMC5516158 | biostudies-literature
UnknownAssessing Ancient DNA Sampling Strategies for Natural Selection Inference in Humans Using Allele Frequency Time Series Data.
Not available
S-EPMC12862635 | biostudies-literature
UnknownQuantiNemo 2: a Swiss knife to simulate complex demographic and genetic scenarios, forward and backward in time.
Not available
S-EPMC6394393 | biostudies-literature
TranscriptomicsInfluence of Deoxynivalenol-contaminated diet on the liver gene expression of chicken.
The mycotoxin deoxynivalenol (DON) is a secondary metabolite from Fusarium species and is frequently present on wheat and other cereals. The main effects of DON are a reduction of the feed intake and reduced weight gain of broilers. At the molecular level DON binds to the 60S ribosomal subunit and i...
ORGANISM(S): Gallus gallus 
2011-11-05 | E-GEOD-25185 | biostudies-arrayexpress
UnknownIdentification of drug-like molecules targeting the ATPase activity of dynamin-like EHD4.
Not available
S-EPMC11285977 | biostudies-literature
TranscriptomicsTranscriptome response of Methanobrevibacter ruminantium to lauric acid in cell culture.
Medium chain fatty acids (MCFA) have been shown to inhibit methanogenesis, disrupt the cell envelope, and decrease survival of Methanobrevibacter ruminantium M1 in a dose-, time-, and protonation level dependent way. However, the exact mechanisms behind these observations are still unknown. Althoug...
ORGANISM(S): Methanobrevibacter ruminantium 
2016-06-01 | E-GEOD-81199 | biostudies-arrayexpress
UnknownGenetic lineage tracing of targeted cell populations during enthesis healing.
Not available
S-EPMC6320286 | biostudies-literature
UnknownCan a Point-of-Care Troponin I Assay be as Good as a Central Laboratory Assay? A MIDAS Investigation.
Not available
S-EPMC4940482 | biostudies-literature
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