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TranscriptomicsFactors underlying variable DNA methylation in a human community cohort
Epigenetics is emerging as an attractive mechanism to explain the persistent genomic embedding of early-life experiences. Tightly linked to chromatin, which packages DNA into chromosomes, epigenetic marks primarily serve to regulate the activity of genes. DNA methylation is the most accessible and c...
ORGANISM(S): Homo sapiens 
2012-10-10 | E-GEOD-37008 | biostudies-arrayexpress
TranscriptomicsEpigenetic Vestiges of Early Developmental Adversity: Child Stress Exposure and Adolescent DNA Methylation
Fifteen-year-old adolescents (N = 109) in a longitudinal study of child development were recruited to examine differences in DNA methylation in relation to parent reports of adversity during the adolescents’ infancy and preschool periods. Microarray technology applied to 28,000 cytosine–guanine dinu...
ORGANISM(S): Homo sapiens 
2011-05-30 | E-GEOD-25892 | biostudies-arrayexpress
TranscriptomicsDistinct DNA methylation patterns of cognitive impairment and Trisomy 21 in Down Syndrome
The presence of an extra whole or part of chromosome 21 in people with Down syndrome (DS) is associated with multiple neurological changes, including pathological aging that often meets the criteria for Alzheimer’s Disease (AD). While the mechanism underlying these changes is unknown, it has been hy...
ORGANISM(S): Homo sapiens 
2014-01-02 | E-GEOD-50586 | biostudies-arrayexpress
UnknownVentilation strategies and risk factors for intraoperative respiratory critical events and postoperative pulmonary complications in neonates and small infants: a secondary analysis of the NECTARINE cohort<sup>☆</sup>.
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S-EPMC12597469 | biostudies-literature
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