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TranscriptomicsThe miRNA pathway controls rapid changes in activity-dependent synaptic structure at the Drosophila melanogaster neuromuscular junction (miRNA array)
It is widely accepted that long-term changes in synapse structure and function are mediated by rapid activity-dependent gene transcription and new protein synthesis. A growing amount of evidence suggests that the microRNA (miRNA) pathway plays an important role in coordinating these processes. Despi...
ORGANISM(S): Drosophila melanogaster 
2013-02-01 | E-GEOD-43943 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse neuromuscular junction laser dissected at various time points vs. normal
NMJ Junction various time points normal C57BL10 LCM mRNA
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-2394 | biostudies-arrayexpress
TranscriptomicsThe miRNA pathway controls rapid changes in activity-dependent synaptic structure at the Drosophila melanogaster neuromuscular junction (RT-PCR)
It is widely accepted that long-term changes in synapse structure and function are mediated by rapid activity-dependent gene transcription and new protein synthesis. A growing amount of evidence suggests that the microRNA (miRNA) pathway plays an important role in coordinating these processes. Despi...
ORGANISM(S): Drosophila melanogaster 
2013-02-01 | E-GEOD-43944 | biostudies-arrayexpress
TranscriptomicsThe miRNA pathway controls rapid changes in activity-dependent synaptic structure at the Drosophila melanogaster neuromuscular junction
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2013-02-01 | E-GEOD-43945 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of neuromuscular junction during degeneration and regeneration of axon terminal
The neuromuscular junction (NMJ) is a specialized tripartite synapse composed of the motor axon terminal, covered by perisynaptic Schwann cells (PSCs), and the muscle fibre, separated by a basal lamina. It is exposed to different kind of injures such as mechanical traumas, pathogens including neurot...
ORGANISM(S): Mus musculus 
2017-05-30 | E-MTAB-5730 | biostudies-arrayexpress
TranscriptomicsModeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs
Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by mutations of the survival of motor neuron 1 (SMN1) gene. In the pathogenesis of SMA, pathological changes of the neuromuscular junction (NMJ) precede the motor neuronal loss. Therefore, it is critical to evaluate the NMJ formed by S...
ORGANISM(S): Homo sapiens 
2015-01-31 | E-GEOD-65470 | biostudies-arrayexpress
GenomicsFibroadipogenic Progenitor Regulates Neuromuscular Junction by Secreting Novel Protein Granzyme E
Fibroadipogenic Progenitor Regulates Neuromuscular Junction by Secreting Novel Protein Granzyme E
PRJNA821082 | ENA
TranscriptomicsModeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs (RNA-Seq)
Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by mutations of the survival of motor neuron 1 (SMN1) gene. In the pathogenesis of SMA, pathological changes of the neuromuscular junction (NMJ) precede the motor neuronal loss. Therefore, it is critical to evaluate the NMJ formed by S...
ORGANISM(S): Homo sapiens 
2015-02-03 | E-GEOD-65508 | biostudies-arrayexpress
GenomicsTemporal transcriptomics of human 3D neuromuscular cultures reveal key signatures of neuromuscular junction development
Temporal transcriptomics of human 3D neuromuscular cultures reveal key signatures of neuromuscular junction development
PRJNA1266181 | ENA
TranscriptomicsWide-ranging analysis of microRNA profiles in sporadic amyotrophic lateral sclerosis using next-generation sequencing
miRNAs has an important role in the diagnosis and treatment of amyotrophic lateral sclerosis. we aimed to profile dysregulation of miRNAs in ALS blood and neuromuscular junction as well as healthy blood control by Next Generation Sequencing (NGS). The expression of three up-regulated miRNAs, as miR-...
ORGANISM(S): Homo sapiens 
2018-12-12 | E-MTAB-7073 | biostudies-arrayexpress
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