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Total RNA sequencing in neuroprogenitors after SMG6 deletion
WNT activation and TGFβ-smad inhibition potentiate stemness of mammalian auditory neuroprogenitors for high throughput generation of functional auditory neurons in vitro
We have previously identified and characterized the phoenix auditory neuroprogenitors (ANPGs) as highly proliferative progenitor cells isolated from the A/J mouse cochlea. In the present study, we aimed at identifying signaling pathways responsible for the intrinsic high stemness of phoenix ANPGs. A...
ORGANISM(S): Mus musculus 
Characterization of SETBP1-deficient hESCs in vitro differentiated towards cortical neuroprogenitors and neurons
Sphere-forming progenitor cells can be isolated from the fetal and adult mammalian inner ear and give rise to inner ear specific cell types in vitro. Here, we provide phenotypical and functional characterization of a new pool of auditory progenitors as sustainable source for sphere-derived auditory ...
ORGANISM(S): Mus musculus 
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