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TranscriptomicsGenome-wide characterization of light-regulated genes in Neurospora crassa
RNA-seq from Neurospora crassa at 5 time points of light induction, with 2 replicates for each, totalling 10 samples RNA-seq from Neurospora crassa at 5 time points of light induction, with 2 replicates for each, totalling 10 samples
ORGANISM(S): Neurospora crassa 
2014-08-01 | E-GEOD-53534 | biostudies-arrayexpress
ProteomicsLSD1 Prevents Aberrant Heterochromatin Formation in Neurospora crassa
Heterochromatin is a specialized form of chromatin that restricts access to DNA and inhibits genetic processes, including transcription and recombination. In Neurospora crassa, constitutive heterochromatin is characterized by trimethylation of lysine 9 on histone H3, hypoacetylation of histones, and...
ORGANISM(S): Neurospora crassa 
2021-07-21 | PXD017300 | Pride
Immunoprecipitation mass spectrometry Lysine-specific demethylase Neurospora crassa Heterochromatin 
TranscriptomicsInduction of lignocellulose-degrading enzymes in Neurospora crassa by cellodextrins
Transcriptional profiling with next-generation sequencing methods demonstrated that a Neurospora crassa mutant with the three most highly expressed beta-glucosidase genes deleted had a transcriptional response to cellobiose similair to that of wild type N. crassa exposed to cellulose. N. crassa was ...
ORGANISM(S): Neurospora crassa OR74A 
2012-04-04 | E-GEOD-36719 | biostudies-arrayexpress
TranscriptomicsDeciphering regulatory mechanisms associated with hemicellulose degradation in Neurospora crassa
Hemicellulose, the second most abundant plant biomass fraction after cellulose, is widely viewed as a potential feedstock for the production of liquid fuels and other value-added materials. Degradation of hemicellulose by filamentous fungi requires production of many different enzymes, which are ind...
ORGANISM(S): Neurospora crassa 
2012-03-26 | E-GEOD-34098 | biostudies-arrayexpress
TranscriptomicsTranscriptional comparison of the filamentous fungus Neurospora crassa growing on three major monosaccharides D-glucose, D-xylose and L-arabinose
D-glucose, D-xylose and L-arabinose are three major monosaccharides in the plant cell wall. Complete utilization of all three sugars is still a bottleneck for second-generation cellulolytic bioethanol production, especially for L-arabinose. However, little is known about the gene expression profiles...
ORGANISM(S): Neurospora crassa 
2014-03-17 | E-GEOD-51091 | biostudies-arrayexpress
TranscriptomicsA comparative systems analysis of polysaccharide-elicited responses in Neurospora crassa reveals carbon source-specific cellular adaptations
Filamentous fungi are powerful producers of hydrolytic enzymes for the deconstruction of plant cell wall polysaccharides. However, the central question of how these sugars are perceived in the context of the complex cell wall matrix remains largely elusive. To address this question in a systematic f...
ORGANISM(S): Neurospora crassa OR74A 
2013-11-27 | E-GEOD-42692 | biostudies-arrayexpress
TranscriptomicsMolecular characterization of a cryptochrome in Neurospora crassa
Cryptochromes were identified in plants and animals where they function as either photoreceptors or circadian clock components. In the filamentous fungus Neurospora, the biological function of cryptochrome has not yet been explored. Here, we demonstrate that Neurospora crassa cryptochrome (Nc cry) i...
ORGANISM(S): Neurospora crassa 
2010-06-05 | E-GEOD-14909 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of wild type Neurospora crassa cells treated with novel antifungal agents
Purpose: Evaluate the transcriptional profile of Neurospora crassa cells treated with a group of novel antifungal compounds Methods: Conidial suspensions were obtained and 1 x 106 cells/ml incubated in minimal medium for 6 hours (26ºC, 140 rpm, constant light) followed by the addition of the indica...
ORGANISM(S): Neurospora crassa 
2015-11-25 | E-GEOD-53040 | biostudies-arrayexpress
ProteomicsProteome-Wide Analyses Reveal Diverse Functions of Acylation Proteins in Neurospora crassa
Quantitative acetyl-proteomics, a newly identified post-translational modification, is known to regulate transcriptional activity in different organisms. Neurospora crassa is a model ascomycete fungus maintained for biochemistry and molecular biology research; however, extensive studies of the funct...
ORGANISM(S): Neurospora crassa 
2021-01-26 | PXD022001 | Pride
Neurospora crassa  quantitative acetyl-proteomics  acetylated proteins  protein-protein interaction 
ProteomicsTOM core complex - Cryo-EM Structure of the TOM Core Complex from Neurospora crassa
The structure of the TOM-complex from Neurospora crassa was characterized using single particle electron microscopy. In order to unambigously identify and characterize the constituting subunits and exclude the presence of previously uncharacterized subunits, the samples were analyzed using proteolyt...
ORGANISM(S): Neurospora crassa 
2017-08-16 | PXD006827 | Pride
Tom Neurospora crassa 
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