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MetabolomicsNeurotransmitter acetylcholine mediates the mummification of Ophiocordyceps sinensis-infected Thitarodes xiaojinensis larvae (Lipidome data)

Parasites can manipulate host behavior to facilitate parasite transmission. One such host-pathogen interaction occurs between the fungus Ophiocordyceps sinensis (O. sinensis) and the ghost moth Thitarodes xiaojinensis. O. sinensis is involved in the mummification process of infected host larvae. ...

2024-08-05 | MTBLS9930 | MetaboLights
MetabolomicsNeurotransmitter acetylcholine mediates the mummification of Ophiocordyceps sinensis-infected Thitarodes xiaojinensis larvae (Metabolome data)

Parasites can manipulate host behavior to facilitate parasite transmission. One such host-pathogen interaction occurs between the fungus Ophiocordyceps sinensis (O. sinensis) and the ghost moth Thitarodes xiaojinensis. O. sinensis is involved in the mummification process of infected host larvae. ...

2024-08-05 | MTBLS9929 | MetaboLights
MetabolomicsSMN deficiency perturbs monoamine neurotransmitter metabolism in spinal muscular atrophy

Beyond motor neuron degeneration, homozygous mutations in the survival motor neuron 1 (SMN1) gene cause multiorgan and metabolic defects in patients with spinal muscular atrophy (SMA). However, the precise biochemical features of these alterations and the age of onset in the brain and peripheral ...

2023-11-27 | MTBLS8784 | MetaboLights
MetabolomicsBifidobacterium animalis subsp. lactis BD1 restores neurotransmitter homeostasis in chronically stressed mice via tryptophan metabolic reprogramming

Background: Chronic psychological stress is a major precipitating factor for neuropsychiatric disorders, yet the underlying mechanisms remain incompletely understood. The gut-brain axis has emerged as a critical regulator of mood and behavior, but how specific commensal microbes modulate host neu...

2025-10-23 | MTBLS13208 | MetaboLights
MetabolomicsAnalysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors

Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea in children and adults in endemic areas. Gene regulation of ETEC during growth in vitro and in vivo needs to be further evaluated, and here we describe the full transcriptome and metabolome of ETEC dur...

2022-07-15 | MTBLS3540 | MetaboLights
ModelsNeurotransmitter Signaling Pathway
Background A Boolean network is a simple computational model that may provide insight into the overall behavior of genetic networks and is represented by variables with two possible states (on/off), of the individual nodes/genes of the network. In this study, a Boolean network model has been used t...
2202 | Cell Collective
GenomicsCo-targeting neurotransmitter signaling and CDK9 to treat diffuse midline glioma [RNA-seq]
Co-targeting neurotransmitter signaling and CDK9 to treat diffuse midline glioma [RNA-seq]
PRJNA1415112 | ENA
GenomicsCo-targeting neurotransmitter signaling and CDK9 to treat diffuse midline glioma [CUT&RUN]
Co-targeting neurotransmitter signaling and CDK9 to treat diffuse midline glioma [CUT&RUN]
PRJNA1411835 | ENA
GenomicsCo-targeting neurotransmitter signaling and CDK9 to treat diffuse midline glioma [ATAC-Seq]
Co-targeting neurotransmitter signaling and CDK9 to treat diffuse midline glioma [ATAC-Seq]
PRJNA1406781 | ENA
GenomicsScRNAseq - Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration
ScRNAseq - Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration
PRJNA678691 | ENA
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