Neutralizing antibody

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Unknown (11339)
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Organisms

Homo sapiens (193)
Mus musculus (191)
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synthetic construct (1)
adeno-associated virus 5 (1)
cellular organisms (1)

Organisms

Mus musculus (170)
Homo sapiens (124)
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Severe acute respiratory syndrome coronavirus 2 (7)
Human immunodeficiency virus 1 (5)
Rattus (3)
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unidentified (1)
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human gut metagenome (1)

Repository

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Tissue

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Cell suspension culture (1)
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Disease

COVID-19 (5)
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"colon adenocarcinoma, acterial infection" (1)
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Technology Type

Mass Spectrometry (36)
Shotgun proteomics (17)
Bottom-up proteomics (7)
Affinity purification coupled with mass spectrometry proteomics (5)
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Data-dependent acquisition (3)
Mass spectrometry (2)
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Instrument Platform

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2005 (1)

CHEBI ID

CHEBI:229268 (1)
CHEBI:62346 (1)
CHEBI:37714 (1)
CHEBI:18040 (1)
CHEBI:196466 (1)
CHEBI:140999 (1)
CHEBI:89267 (1)
CHEBI:35045 (1)
CHEBI:49026 (1)
CHEBI:5445 (1)
CHEBI:53455 (1)
CHEBI:131381 (1)
CHEBI:16796 (1)
CHEBI:86369 (1)
CHEBI:15670 (1)
CHEBI:37655 (1)
CHEBI:83051 (1)
CHEBI:28125 (1)
CHEBI:65136 (1)
CHEBI:42682 (1)
CHEBI:43419 (1)
CHEBI:17173 (1)
CHEBI:21077 (1)
CHEBI:18314 (1)
CHEBI:28194 (1)
CHEBI:18101 (1)
CHEBI:16217 (1)
CHEBI:49059 (1)
CHEBI:75108 (1)
CHEBI:21553 (1)

Metabolite Name

Norvaline (2)
Indoleacetic acid (2)
N-Acetyl-D-glucosamine (2)
N-Acetylglutamine (2)
Citrulline (2)
Nicotinic acid (2)
Carnitine (2)
Phenyllactic acid (2)
Adrenic acid (2)
Cholic acid (2)
Glycocholic acid (2)
2-Furoic acid (2)
Pipecolic acid (2)
Asparagine (2)
Nonadeca-10Z-enoic acid (1)
6-Octadecylenic acid (1)
Bishomo-gamma-linolenic acid (1)
N-Acetyl-alpha-neuraminic acid (1)
3-Aminobenzoic acid (1)
5-Amino-levulinic acid (1)
(4Z,7Z,10Z,13Z)-15-{3-[(2Z)-Pent-2-en-1-yl]oxiran-2-yl}pentadeca-4,7,10,13-tetraenoylcarnitine (1)
Methyl(acetoxymethyl)nitrosamine (1)
5alpha-Pregnan-3beta,20beta-diol 20-sulfate (1)
PC(18_1(11Z)_14_0) (1)
PC(16_0_20_4(5Z,8Z,11Z,14Z)) (1)
Gamma-glutamylglutamate (1)
PC(14_1(9Z)_22_1(13Z)) (1)
4,5-Dimethyl-2-heptyloxazole (1)
4-(Nitrosomethylidene)-1-[[4-(nitrosomethylidene)pyridin-1-yl]methoxymethyl]pyridine (1)
Dimethyl maleate (1)

IsPrivate

False (2)

First Public Date

2025 (85)
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2022 (59)
2023 (49)
2021 (36)
2014 (30)
2019 (25)
2020 (20)
2017 (13)
2016 (13)
2018 (6)
2013 (4)
2015 (3)

Classification

viruses (20)

Modelling Approach

Ordinary differential equation model (2)

Study type

Transcription profiling by array (97)
RNA-seq of coding RNA (11)
ChIP-seq (7)
RNA-seq of coding RNA from single cells (6)
Unknown experiment type (4)
Animal - High-throughput sequencing (1)
Genotyping by array (1)
Transcription profiling by RT-PCR (1)
Single nucleus RNA sequencing (1)
DNA-seq (1)
Proteomic profiling by array (1)

Release Date

2022 (1873)
2021 (1466)
2023 (1272)
2024 (927)
2025 (884)
2020 (791)
2019 (534)
2018 (500)
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2017 (492)
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2013 (280)
2012 (230)
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2010 (133)
2009 (124)
2026 (108)
2008 (102)
2007 (70)
2005 (41)
2006 (41)
2004 (28)
2003 (18)
2000 (18)
1999 (12)
2002 (11)
1998 (6)
2001 (5)
1997 (2)

Lab affiliation

Associate Professor, University of Washington (2)
King's College London British Heart Foundation Centre, School of Cardiovascular Medicine and Sciences, King's College London, London, UK. (2)
Assistant Professor, Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA (1)
Associate Professor, Department of Pathology, Faculty of Medicine, The University of Hong Kong (1)
Bioinformatics Solutions Inc., Waterloo, Ontario, Canada (1)
Biozentrum, University of Basel, Switzerland (1)
Center for Proteomics and Metabolomics, Leiden University Medical Center, The Netherlands (1)
Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria (1)
Department of Biochemistry, University of Washington, Seattle WA USA (1)
Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA (1)
Department of Chemistry, University of Washington, Seattle, Washington 98195, United States (1)
Department of Integrated Immunobiology Duke School of Medicine Durham, NC, USA (1)
Department of Microbiology & Immunology, National University of Singapore, Singapore (1)
Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Box 280, S-171 77 Stockholm, Sweden. (1)
Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037 United States (1)
Director of Biochemistry, Vaccine Company, Inc (1)
Division of Infection Medicine, Department of Clinical Sciences, Faculty of Medicine, Lund University, Klinikgatan 26, 222 42 Lund, Sweden (1)
Hannover Medical School, Department of Cardiology and Angiology, Division of Molecular and Translational Cardiology, Hans Borst Center for Heart and Stem Cell Research, Hannover (1)
IICB-Translational Research Unit of Excellence, CSIR-Indian Institute of Chemical Biology,Kolkata, India (1)
ISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain (1)
Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland. (1)
Institute of Biomedical Science, Academia Sinica, Taiwan (1)
Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China. (1)
MSAP UAR 3290 CNRS (1)
Mass Spectrometry Technology Access Center at the McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA. (1)
National Center for Microbiology, Instituto de Salud Carlos III. Majadahonda, Madrid, Spain (1)
School of Medicine, Shanghai University, Shanghai 200444, China. (1)
Science for Life Laboratory; Department of Oncology Pathology, Karolinska Institute, Stockholm, Sweden (1)
State Key Laboratory of National Security Specially Needed Medicines, Beijing 100039, China. (1)
Texas Tech University (1)

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Absolute quantification of serum cytokines and metabolome reveals the glycylproline regulating antibody-fading in convalescent COVID-19 patients

The COVID-19 pandemic has incurred tremendous costs worldwide and is still threatening public health in the 'new normal'. The association between neutralizing antibody levels and metabolic alterations in convalescent patients with COVID-19 is still poorly understood. In the present work, we condu...

2024-08-26 | MTBLS3305 | MetaboLights

Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.

Not available

S-EPMC6019700 | biostudies-literature

Complement activation by AAV-neutralizing antibody complexes

IP-MS analysis of AAV9 empty capsid protein-protein interactions with serum from healthy human donors.

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2023-03-09 | MSV000091454 | MassIVE

Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach.

Not available

S-EPMC5528178 | biostudies-literature

Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development.

Not available

S-EPMC5613947 | biostudies-literature

Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1.

Not available

S-EPMC3386053 | biostudies-literature

Potent neutralizing antibodies against SARS-CoV-2

The COVID-19 pandemic urgently needs therapeutic and prophylactic interventions. Here we report the rapid identification of SARS-CoV-2 neutralizing antibodies by high-throughput single-cell RNA and VDJ sequencing of antigen-enriched B cells from 60 convalescent patients.

EGAS00001004412 | EGA

Structure-guided alterations of the gp41-directed HIV-1 broadly neutralizing antibody 2F5 reveal new properties regarding its neutralizing function.

Not available

S-EPMC3400562 | biostudies-literature

Effects of HGF neutralizing antibody on three-dimensional co-culture of periodontitis-associated fibroblasts (PAF)

PRJNA577823 | ENA

Restoring the potency of neutralizing antibody via guided hypermutation with hyper-antibody editor

PRJNA1182716 | ENA

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12322 Results

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