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TranscriptomicsExpression data from breast cancer cell lines with various colony-forming ability
Cultured cancer cells exhibit substantial phenotypic heterogeneity when measured in a variety of ways such as sensitivity to drugs or the capacity to grow under various conditions. Among these, the ability to exhibit anchorage-independent cell growth (colony forming capacity in semisolid media), ha...
ORGANISM(S): Homo sapiens 
2009-04-10 | E-GEOD-15026 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of Ras mutants.
Gene expression profiles were collected from HEK-HT cells expressing H-Ras with Ras-activating (G12V), Raf-activating (G12V,T35S), RalGEF-activating (G12V,E37G), or PI3K-activating (G12V,Y40C) mutations. Keywords: Comparison of Ras pathway components. THX=control; 12V=G12V mutation; 35S=G12V,T35S m...
ORGANISM(S): Homo sapiens 
2009-02-21 | E-GEOD-14934 | biostudies-arrayexpress
TranscriptomicsGenetic Heterogeneity in Mouse Mammary Tumors
Human cancers result from a complex series of genetic alterations resulting in heterogeneous disease states. Dissecting this heterogeneity is critical for understanding underlying mechanisms and providing opportunities for therapeutics matching the complexity. Mouse models of cancer have generally b...
ORGANISM(S): Mus musculus 
2010-03-03 | E-GEOD-15904 | biostudies-arrayexpress
TranscriptomicsA 50-Gene Predictor of Recurrence as a Guide to Therapy in Early-Stage Colon Cancer.
Gene expression profiles reflect unique aspects of individual biologic phenotypes and may characterize the heterogeneity of solid tumors. Using previously-described methodologies that employ DNA microarray data, a 50-gene expression profile (metagene) that predicts risk of recurrence in early stage ...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-10402 | biostudies-arrayexpress
UnknownBaseline Features and Reasons for Nonparticipation in the Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM) Study, a Colorectal Cancer Screening Trial.
Not available
S-EPMC10336619 | biostudies-literature
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