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MetabolomicsA multi-omic analysis of birthweight in newborn cord blood reveals new underlying mechanisms related to cholesterol metabolism

BACKGROUND: Birthweight reflects in utero exposures and later health evolution. Despite existing studies employing high-dimensional molecular measurements, the understanding of underlying mechanisms of birthweight remains limited.

METHODS: To investigate th...

2020-06-19 | MTBLS1684 | MetaboLights
MetabolomicsPlasma 1H-NMR metabolic and amino acid profiles of newborn piglets from two lines divergently selected for residual feed intake

Together with environmental factors, physiological maturity at birth is a major determinant for neonatal survival and postnatal development in mammalian species. Maturity at birth is the outcome of complex mechanisms of intra-uterine development and maturation during the end of gestation. In pig ...

2023-02-16 | MTBLS2137 | MetaboLights
MetabolomicsLipidomics of Near-Term Fetal and Newborn Sheep Cardiac Tissue (part-II)
Not available
ORGANISM(S): Ovis aries 
ST001061 | MetabolomicsWorkbench
MetabolomicsNMR Metabolomics of Near-Term Fetal and Newborn Sheep Cardiac Tissue (part-I)
Not available
ORGANISM(S): Ovis aries 
ST001060 | MetabolomicsWorkbench
TranscriptomicsWild-type and COUP-TFI-/- newborn inner ear microarrays
In order to establish a list of candidate direct COUP-TFI gene targets in the inner ear, we analyzed the differential gene expression profiles of the wild-type and the COUP-TFI–/– P0 inner ears. We performed a total of 8 microarray experiments using Affymetrix MG-U74Av2 chips, including 2 biol...
ORGANISM(S): Mus musculus 
2010-06-08 | E-GEOD-16744 | biostudies-arrayexpress
TranscriptomicsPrenatal arsenic exposure and the epigenome: altered gene expression profiles in newborn cord blood
The Biomarkers of Exposure to ARsenic (BEAR) pregnancy cohort in Gómez Palacio, Mexico was recently established to better understand the impacts of prenatal exposure to inorganic arsenic (iAs). In this study, we examined a subset (n = 40) of newborn cord blood samples for microRNA (miRNA) expression...
ORGANISM(S): Homo sapiens 
2014-01-22 | E-GEOD-48354 | biostudies-arrayexpress
GenomicsThe DNA methylomes of a newborn and a centenarian
We have developed Whole Genome Bisulfite Sequencing (WGBS) of a newborn and a centenarian to address the epigenetic drifts in human aging, which might be an alternative pathway to explain the age-associated alterations. In addition, we have analyzed the methylome of a middle-age donor (26 years). Ex...
ORGANISM(S): Homo sapiens 
2012-06-13 | E-GEOD-31263 | biostudies-arrayexpress
TranscriptomicsPrenatal arsenic exposure and the epigenome: altered miRNA expression profiles in newborn cord blood
The Biomarkers of Exposure to ARsenic (BEAR) pregnancy cohort in Gómez Palacio, Mexico was recently established to better understand the impacts of prenatal exposure to inorganic arsenic (iAs). In this study, we examined a subset (n = 40) of newborn cord blood samples for microRNA (miRNA) expression...
ORGANISM(S): Homo sapiens 
2014-01-22 | E-GEOD-48353 | biostudies-arrayexpress
MetabolomicsMaternal Hypoxemia and oxidative stress in the fetus, newborn, and adult. exercise training for peripheral artery disease
Not available
ORGANISM(S): Ovis aries 
ST000872 | MetabolomicsWorkbench
TranscriptomicsMouse gestational protein restriction: Newborn offspring liver and hindleg muscle
Gestational protein restriction is a model for low birth size. We hypothesized that taurine supplementation would protect against changes in newborn liver and muscle caused by a maternal low protein diet. Pregnant mouse dams were subjected to different diet schemes from day 1 of pregnancy until birt...
ORGANISM(S): Mus musculus 
2009-11-07 | E-GEOD-12730 | biostudies-arrayexpress
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