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ProteomicsConcentration determination of >200 proteins in dried blood spots for biomarker discovery and validation
Raw files were created using XCalibur 3.0.63 (Thermo Scientific) software and analysed with Thermo Proteome Discoverer 2.2.0.388 software suite (Thermo Scientific). The raw data files were processed as previously described 26 with the following modifications: the peak lists were submitted to Mascot...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-11-27 | MSV000084629 | MassIVE
ProteomicsOne-Pot Isotope Dilution PRM for Quantitative Protein Heterogeneity in Red Blood Cells
Single cell and low-input cell proteomics to measure cellular heterogeneity remains experimental and requires further refinement for routine application. This study aimed to build on previous protocols to assess the utility of targeted proteomics for measuring heterogeneity in red blood cells (RBCs)...
ORGANISM(S): Homo Sapiens 
2024-02-06 | PXD030875 | panorama
ProteomicsMultiplexed MRM concentration measurements of >200 endogenous proteins in dried blood spots for biomarker discovery and validation
The use of protein biomarkers as surrogates for clinical endpoints requires extensive multilevel validation including development of robust and sensitive assays for precise measurement of protein concentration. Multiple reaction monitoring (MRM), is a well-established methodology that can be used f...
ORGANISM(S): Homo Sapiens 
2020-01-06 | PXD015118 | panorama
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