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MetabolomicsThe phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 inhibitor 3PO is a modulator of neutrophil metabolism, ROS production and NET release
Neutrophils are key effector leukocytes of the innate immune system and play a pivotal role in defending the host against microbial infections. Recent studies have identified a crucial link between glycolysis and neutrophil cellular functions. We have investigated in human neutrophils, the intricate...
2025-08-14 | MTBLS6215 | MetaboLights
UnknownPretreatment with an anti-CGRP monoclonal antibody attenuates mild TBI-induced tactile hypersensitivity in mice.
Not available
S-EPMC12323213 | biostudies-literature
UnknownA one-transistor organic electrochemical self-sustained oscillator model for neuromorphic networks.
Not available
S-EPMC12501206 | biostudies-literature
UnknownA successful prediction of the record CO2 rise associated with the 2015/2016 El Nino.
Not available
S-EPMC6178439 | biostudies-literature
TranscriptomicsTranscription profiling by array of Drosophila embryonic chordotonal neurons expressing the cato GFP reporter gene construct
Further to a previous transcription profiling experiment using a GFP reporter gene construct expressing the Drosophila proneural gene atonal (Cachero et al. 2011), a later expressing transcription factor and downstream target of ato, cato (cousin of ato) was explored as the GFP reporter in this expe...
ORGANISM(S): Drosophila melanogaster 
2019-02-19 | E-MTAB-7529 | biostudies-arrayexpress
MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
UnknownTranslating advocacy into action: exploring oncology healthcare professionals' awareness and use of the Clinical Oncology Society of Australia position statement on exercise in cancer care.
Not available
S-EPMC12167252 | biostudies-literature
UnknownCytarabine-based induction immunochemotherapy in the front-line treatment of older patients with mantle cell lymphoma.
Not available
S-EPMC6753133 | biostudies-literature
UnknownActivation of atypical protein kinase C by sphingosine 1-phosphate revealed by an aPKC-specific activity reporter.
Not available
S-EPMC6657501 | biostudies-literature
UnknownAcquired <i>RAD51C</i> Promoter Methylation Loss Causes PARP Inhibitor Resistance in High-Grade Serous Ovarian Carcinoma.
Not available
S-EPMC12593227 | biostudies-literature
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