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Stimulation of the mouse hindlimb via the sciatic nerve was used to induce contractions for 4 hours to investigate acute muscle gene activation in a model of muscle phenotype conversion. Initial force production (1.6 + 0.1 g/g body weight) declined 45% within 10 min and was maintained for the remain...
ORGANISM(S): Mus musculus 
WTCCC2 samples from 1958 British Birth Cohort
WTCCC2 samples from Type 2 Diabetes Cohort
WTCCC2 samples from Hypertension Cohort
WTCCC2 samples from Coronary Artery Disease Cohort
Genomewide association studies (GWAS) have proven a powerful hypothesis-free method to identify common disease-associated variants. Even quite large GWAS, however, have only at best identified moderate proportions of the genetic variants contributing to disease heritability. To provide cost-effectiv...
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