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GenomicsNFKB2 in PDAC
Role of NFKB2 in pancreatic ductal adenocarcinama (PDAC)
PRJEB30882 | ENA
GenomicsNFKB1 and NFKB2 differently modulate transcriptional profile of MT-2 cells
NFKB1 and NFKB2 differently modulate transcriptional profile of MT-2 cells
PRJEB67351 | ENA
TranscriptomicsNfkb2 deficiency and its impact on the murine small intestinal mucosa
The alternative (non-canonical) nuclear factor-kappa B (NF-κB) signalling pathway predominantly regulates the function of the p52/RelB heterodimer. Germline Nfkb2 deficiency in mice leads to loss of p100/p52 protein and offers protection against a variety of gastrointestinal conditions, such as azox...
ORGANISM(S): Mus musculus 
2022-07-31 | E-MTAB-11018 | biostudies-arrayexpress
TranscriptomicsNFKB1 and NFKB2 differently modulate transcriptional profile of MT-2 cells
To investigate the effects of NFKB signaling, RNA-seq analysis was performed on both Jurkat and MT-2 cells. It was observed that either NFKB1 or NFKB2 knockout could alter the gene expression profile in MT-2 cells compared to Jurkat cells. Gene expression profiles of NFKB1/NFKB2 knockout Jurkat cell...
ORGANISM(S): Homo sapiens 
2023-11-01 | E-MTAB-13408 | biostudies-arrayexpress
GenomicsNFKB2 mediates colorectal cancer cell immune escape and metastasis in a STAT2/PD-L1-dependent manner
NFKB2 mediates colorectal cancer cell immune escape and metastasis in a STAT2/PD-L1-dependent manner
PRJNA1051964 | ENA
GenomicsNfkb2 deficiency and its impact on the murine small intestinal mucosa
Nfkb2 deficiency and its impact on the murine small intestinal mucosa
PRJEB47948 | ENA
TranscriptomicsNFKB2 mediates colorectal cancer cell immune escape and metastasis in a STAT2/PD-L1-dependent manner
This study systematically analyzed the molecular mechanism and function of nuclear factor kappa B subunit 2 (NFKB2) in colorectal cancer (CRC) to investigate the potential of NFKB2 as a therapeutic target for CRCTo investigate the potential of NFKB2 as a therapeutic target for colorectal cancer (CRC...
ORGANISM(S): Mus musculus 
2023-12-21 | GSE250065 | GEO
UnknownCombined immune deficiency in a patient with a novel NFKB2 mutation.
Not available
S-EPMC5705040 | biostudies-literature
GenomicsGenome-wide differential binding pattern of NFKB2/p52 under prolonged culture conditions
Genome-wide differential binding pattern of NFKB2/p52 under prolonged culture conditions
PRJNA755535 | ENA
TranscriptomicsTNF-induced gene-expressions in Nfkb2-/- MEFs and its derivatives
As such, TNF triggers the canonical NF-?B pathway to induce a nuclear NF-?B activity composed of the RelA:p50 dimer in WT cells. Nfkb2 encodes p100, which regulates the activity of the RelB NF-?B heterodimers during immune cell-differentiation via the noncanonical pathway. Our biochemical analyses r...
ORGANISM(S): Mus musculus 
2019-06-13 | GSE99980 | GEO
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