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TranscriptomicsGlobal changes in gene expression during sub-zero acclimation of three Arabidopsis thaliana accessions
During cold acclimation plants increase their freezing tolerance in response to low non-freezing temperatures. This is accompanied by many physiological, biochemical and molecular changes that have been extensively investigated. In addition, many cold acclimated plants become more freezing tolerant ...
ORGANISM(S): Arabidopsis thaliana 
2014-03-12 | E-GEOD-55835 | biostudies-arrayexpress
TranscriptomicsReplacement of the Saccharomyces cerevisiae acetyl-CoA synthetases by alternative pathways for cytosolic acetyl-CoA synthesis
Cytosolic acetyl-coenzyme A is a precursor for many biotechnologically relevant compounds produced by Saccharomyces cerevisiae. In this yeast, cytosolic acetyl-CoA synthesis and growth strictly depend on expression of either the Acs1 or Acs2 isoenzyme of acetyl-CoA synthetase (ACS). Since hydrolysis...
ORGANISM(S): Saccharomyces cerevisiae 
2013-11-21 | E-GEOD-47983 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of HC11 mammary epithelial cell strains stably expressing different variants of the transcriptional regulator megakaryoblastic leukemia-1 (Mkl1)
We have previously shown that HC11 mammary epithelial cells react strongly to the overexpression of megakaryoblastic leukemia-1 (Mkl1) with induction of tenascin-C expression. The present study was designed to find genes co-regulated with tenascin-C by Mkl1 in a SAP domain-dependent manner and witho...
ORGANISM(S): Mus musculus 
2014-02-06 | E-GEOD-44907 | biostudies-arrayexpress
TranscriptomicsMolecular analysis of clonal B cells in hepatitis C virus related-lymphoproliferation
Comparison of molecular pathways in clonal and non-clonal marginal zone B cells in Hepatitis C virus patients
ORGANISM(S): Homo sapiens 
2011-02-15 | E-MTAB-521 | biostudies-arrayexpress
TranscriptomicsEffects of pregnancy and progesterone supplementation on endometrial gene expression in cattle
An increase in circulating progesterone (P4) concentrations is associated with increased pregnancy success in beef and dairy cattle. Our objective was to ascertain differential effects of elevated P4 concentrations following conception on endometrial gene expression in beef heifers on Days 5, 7, 13 ...
ORGANISM(S): Bos taurus 
2011-10-17 | E-GEOD-33030 | biostudies-arrayexpress
TranscriptomicsEngineering acetyl-CoA supply: Functional expression of a bacterial pyruvate-dehydrogenase complex in the cytosol of Saccharomyces cerevisiae
The energetic (ATP) cost of biochemical pathways critically determines the maximum yield of metabolites of vital or commercial relevance. Cytosolic acetyl-CoA is a key precursor for biosynthesis in eukaryotes and for many industrially relevant product pathways that have been introduced into Saccharo...
ORGANISM(S): Saccharomyces cerevisiae 
2014-11-04 | E-GEOD-59814 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human monocyte-derived macrophages infected with HIV-1 or stimulated with interferon-beta, interferon-gamma or lipopolysaccharide
Transcriptional profiling of HIV-1 infected and that of IFNbeta, IFNgamma or LPS stimulated human monocyte derived macrophages.
ORGANISM(S): Homo sapiens 
2009-09-01 | E-MEXP-2032 | biostudies-arrayexpress
TranscriptomicsSugar sweet springtails: On the transcriptional response of Folsomia candida (Collembola) towards desiccation stress
Folsomia candida (Collembola) is able to survive dryer conditions by absorbing water vapour from its surroundings. To unravel the genomic responses underlying this intriguing water-absorption mechanism, we exposed the species to 98.2% Relative Humidity (eight, 27, 53 and 174 hours respectively) and ...
ORGANISM(S): Folsomia candida 
2010-05-06 | E-GEOD-16127 | biostudies-arrayexpress
TranscriptomicsGene expression by Retinoic Acid in mouse Dendritic Cells
The purpose of this study was to determine and clarify the retinoic effect on the gene expression profile for mouse dendritic cells. Dendritic cells were prepared from marrow cells by culturing them for 10 days with GM-CSF (20 ng/ml). These cells were cultured with the following reagents from the ...
ORGANISM(S): Mus musculus 
2013-02-26 | E-GEOD-34324 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of multiple mouse myeloma (MM) cells during intra-medullary progression in the 5T2MM mouse model
Insights into mechanisms involved during intra-medullary myeloma progression could be helpful in the better understanding of this disease and in the development of new therapeutical strategies. Herein gene expression profile of multiple myeloma (MM) cells during intra-medullary progression was inves...
ORGANISM(S): Mus musculus 
2008-03-27 | E-MEXP-186 | biostudies-arrayexpress
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