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UnknownPrediagnostic Plasma 25-Hydroxyvitamin D and Pancreatic Cancer Survival.
Not available
S-EPMC5012662 | biostudies-literature
GenomicsForced Notch2 signaling instructs TLR and BCR responsiveness in B cells [RNA-Seq]
Forced Notch2 signaling instructs TLR and BCR responsiveness in B cells [RNA-Seq]
PRJNA1477801 | ENA
TranscriptomicsmiRNA profiles of brain glioma stem cells and normal neural stem cells
A human microarray comprising 1658 human genome probes was used to evaluate the specific expression of miRNA between brian glioma stem cells (GSC) and normal neural stem cells(NSC). 2 total RNA samples are analyzed, brian glioma stem cells (GSC) and normal neural stem cells(NSC). cell type: brain g...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-41032 | biostudies-arrayexpress
ProteomicsSTUB1 is an intracellular checkpoint for interferon gamma sensing
Immune checkpoint blockade (ICB) leads to durable and complete tumour regression in some patients but in others gives temporary, partial or no response. Accordingly, significant efforts are underway to identify tumour-intrinsic mechanisms underlying ICB resistance. Results from a published CRISPR sc...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-18 | PXD035392 | Pride
Mouse melanoma cell lines 
TranscriptomicsExpression data from TGF-beta treated Panc-1 pancreatic adenocarcinoma cell line
TGF-beta treatment of Panc-1 pancreatic adenocarcinoma cell line on Affymetrix HG_U133_plus_2 arrays; triplicate experiments. The goal of the experiment is to profile temporal gene expression changes during TGF-beta-induced epithelial-mesenchymal transition (EMT). During EMT cancer cells lose their ...
ORGANISM(S): Homo sapiens 
2010-09-03 | E-GEOD-23952 | biostudies-arrayexpress
ProteomicsMulti-omic Evaluation of PLK1 Inhibitor—Onvansertib—in Colorectal Cancer Spheroids
Polo-like kinase 1 (Plk1) is a serine/threonine kinase involved in regulating the cell cycle. It is activated by aurora kinase B along with the cofactors Borealin, INCE, and survivn. Plk1 is involved in the development of resistances to chemotherapeutics such as doxorubicin, taxol, and gemcitabine. ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD054453 | Pride
Colorectal cancer Lipidomics Cell cycle Spheroids Proteomics Spatial lipidomics Plk-1 inhibition Mass spectrometry imaging 
TranscriptomicsTranscriptional profiling of Hoxa9-expanded hematopoietic cells expressing distinct TALE genes
Primary murine hematopoietic cells were retrovirally transduced with Hoxa9 cDNA, expanded in vitro before undergoing secondary infection with the cDNA of Meis1, Prep1 and the Prep1-MC mutant. RNA was extracted and transcriptomes were analyzed. Background corrections and normalisations were performe...
ORGANISM(S): Mus musculus 
2011-09-08 | E-MTAB-671 | biostudies-arrayexpress
ProteomicsRedox Proteome of Skeletal Muscle
Adult and aged mouse gastrocnemius muscle analysed by redox shotgun proteomics, applying a label free quantitative proteomic approach that includes a differential Cysteine labelling step allowing simultaneous identification of up and down regulated proteins between samples and also the identificatio...
ORGANISM(S): Mus musculus (Mouse) 
2014-09-04 | PXD001054 | Pride
Redox Skeletal muscle 
TranscriptomicsThe microRNA expression profile of C2C12 cell upon 72 hours of BMP2 treatment
To identify osteoblast specific miRNAs that can contribute to osteoblastogenesis by post-transcriptionally regulates their targets, BMP2 are treated to C2C12 for 72 hours and performed miRNA microarray. C2C12 cells were treated with vehicles or BMP2 (300 ng/mL) supplemented alpha-MEM media for 72 da...
ORGANISM(S): Mus musculus 
2012-05-02 | E-GEOD-37036 | biostudies-arrayexpress
GenomicsRif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching
DNA double-strand breaks (DSBs) represent a threat to the genome because they can lead to loss of genetic information and chromosome rearrangements. The DNA repair protein p53 binding protein 1 (53BP1) protects the genome by limiting nucleolytic processing of DSBs by a mechanism that requires its ph...
ORGANISM(S): Mus musculus 
2013-03-01 | E-GEOD-42298 | biostudies-arrayexpress
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