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Metabolomics13C glucose labelling studies using 2D NMR is a useful tool for determining ex vivo whole organ metabolism during hypothermic machine perfusion of kidneys
Background: The aim of this study is to determine the feasibility of using Nuclear Magnetic Resonance (NMR) tracer studies (13C-enriched glucose) to detect ex vivo de novo metabolism in the perfusion fluid and cortical tissue of porcine kidneys during hypothermic machine perfusion (HMP). Methods: Po...
2017-10-16 | MTBLS367 | MetaboLights
TranscriptomicsA Short-Term Study Investigating the Estrogenic Potency of Diethylstilbesterol in the Fathead Minnow (Pimephales promelas): Exposure Phase
Diethylstilbestrol (DES) is a synthetic estrogen that has been banned for use in humans, but still is employed in livestock and aquaculture operations in some parts of the world. Detectable concentrations of DES in effluent and surface waters have been reported to range from slightly below 1 to gre...
ORGANISM(S): Pimephales promelas 
2012-09-20 | E-GEOD-36465 | biostudies-arrayexpress
TranscriptomicsA Short-Term Study Investigating the Estrogenic Potency of Diethylstilbesterol in the Fathead Minnow (Pimephales promelas): Recovery phase
Diethylstilbestrol (DES) is a synthetic estrogen that has been banned for use in humans, but still is employed in livestock and aquaculture operations in some parts of the world. Detectable concentrations of DES in effluent and surface waters have been reported to range from slightly below 1 to gre...
ORGANISM(S): Pimephales promelas 
2012-09-20 | E-GEOD-36466 | biostudies-arrayexpress
MetabolomicsNext-generation biomonitoring of the early-life chemical exposome in neonatal and infant development

Exposure to synthetic and natural chemicals is a major environmental risk factor in the etiology of many chronic diseases. Investigating complex co-exposures is necessary for a holistic assessment in exposome-wide association studies. In this work, a sensitive liquid chromatography-tandem mass sp...

2023-10-26 | MTBLS2442 | MetaboLights
UnknownProgress of mesenchymal stem cell therapy for neural and retinal diseases.
Not available
S-EPMC3999769 | biostudies-literature
TranscriptomicsDifferential functional effects of EGF along the human fetal intestine
Transcriptional profiling of small and large intestinal explants cultured in the absence or in the presence of EGF (50 ng/mL). Two-condition experiment, control intestinal explants vs EGF intestinal explants
ORGANISM(S): Homo sapiens 
2012-01-11 | E-GEOD-18367 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analyses of duodenum from wild type and VDR-null mice
As duodenum is an important Vitamin D target organ, transcriptomic analyses were performed in this tissue. We analysed RNA extracted from duodenum of three 10 week-old wild-type and VDR-null mice using the Affymetrix Mouse Gene 2.0 ST.
ORGANISM(S): Mus musculus 
2015-04-16 | E-GEOD-67904 | biostudies-arrayexpress
TranscriptomicsBulk RNA-Seq to study the effects of CENP-A overexpression, p53 status, and X- irradiation treatment in MCF-10-2A cells
We performed bulk RNA-Seq to investigate global transcriptional changes upon overexpression of the centromeric H3 variant CenH3/CENP-A in p53 wild-type and defective cells, and after X-irradiation treatment. We established clonal MCF-10-2A TetOn-CENPA-FLAG-HA cell lines where CENP-A can be reversibl...
ORGANISM(S): Homo sapiens 
2021-03-01 | E-MTAB-9867 | biostudies-arrayexpress
TranscriptomicsS080_BrCaRes_Schneeweiss et al.
In patients with primary breast cancer, neoadjuvant chemotherapy with doxorubicin plus pemetrexed followed by docetaxel (AP-D) is associated with a pathologic complete response (pCR) rate of 16.5%, and doxorubicin plus cyclophosphamide followed by docetaxel (AC-D) is associated with a pCR rate of 20...
ORGANISM(S): Homo sapiens 
2014-02-01 | E-TABM-1186 | biostudies-arrayexpress
ProteomicsProteomic Profiling of Barley Spent Grains
Proteomic profiling was performed on barley spent grain. Spent grain from malted barley and from raw barley supplemented with exogenous enzymes were profiled.
ORGANISM(S): Hordeum vulgare (Barley) 
2018-03-23 | PXD008090 | Pride
Barley Spent grain 
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