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TranscriptomicsA Short-Term Study Investigating the Estrogenic Potency of Diethylstilbesterol in the Fathead Minnow (Pimephales promelas): Exposure Phase
Diethylstilbestrol (DES) is a synthetic estrogen that has been banned for use in humans, but still is employed in livestock and aquaculture operations in some parts of the world. Detectable concentrations of DES in effluent and surface waters have been reported to range from slightly below 1 to gre...
ORGANISM(S): Pimephales promelas 
2012-09-20 | E-GEOD-36465 | biostudies-arrayexpress
TranscriptomicsA Short-Term Study Investigating the Estrogenic Potency of Diethylstilbesterol in the Fathead Minnow (Pimephales promelas): Recovery phase
Diethylstilbestrol (DES) is a synthetic estrogen that has been banned for use in humans, but still is employed in livestock and aquaculture operations in some parts of the world. Detectable concentrations of DES in effluent and surface waters have been reported to range from slightly below 1 to gre...
ORGANISM(S): Pimephales promelas 
2012-09-20 | E-GEOD-36466 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human macrophages from ankylosing spondylitis patients reveals interferon-gamma dysregulation
OBJECTIVE: To determine whether macrophages, a type of cell implicated in the pathogenesis of ankylosing spondylitis (AS), exhibit a characteristic gene expression pattern. METHODS: Macrophages were derived from the peripheral blood of 8 AS patients (median disease duration 13 years [range <1-43 yea...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-11886 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse intestinal epithelial m-ICcl2 cells stimulated with lipopolysaccharide
m-ICcl2 cells (Bens et al., Am. J. Physiol., 1996) were grown for 6 days on collagen coated cell culture flasks in medium as recommended (see ference above). Medium was changed every 48 hours. The cells were mycoplasma tested (PCR) and found negative. The medium and PBS was endotoxin tested (ELISA) ...
ORGANISM(S): Mus Musculus 
2011-08-26 | E-MTAB-355 | biostudies-arrayexpress
TranscriptomicsAnalysis of temporal mRNA expression changes in cultured keratinocytes from Casp-8F/M-bM-^@M-^SK5-Cre and Casp-8F/+K5-Cre mice
Expression of enzymatically inactive caspase-8, or deletion of caspase-8 from basal epidermal keratinocytes, triggers chronic skin inflammation in mice. Unlike similar inflammation resulting from arrest of NF-kB activation in the epidermal cells, the effect induced by caspase-8 deficiency did not de...
ORGANISM(S): Mus musculus 
2009-07-29 | E-GEOD-17345 | biostudies-arrayexpress
UnknownPrediagnostic Plasma 25-Hydroxyvitamin D and Pancreatic Cancer Survival.
Not available
S-EPMC5012662 | biostudies-literature
TranscriptomicsA single cell atlas of frozen shoulder capsule identifies features associated with inflammatory fibrosis resolution (Bulk RNA-seq of capsular fibroblasts co-cultured with MDMs)
Bulk transcriptomic data of shoulder capsule fibroblasts isolated from frozen shoulder co-cultured with Dexamethasone (DEX) or LPS treated monocyte-derived macrophages (MDM), which were isolated from blood cones and stimulated with M-CSF, for 72 hours. The stimulated MDMs have been characterised as ...
ORGANISM(S): Homo sapiens 
2023-10-02 | E-MTAB-12312 | biostudies-arrayexpress
TranscriptomicsThreshold of Biologic Response of the Small Airway Epithelium to Low Levels of Tobacco Smoke
Background: Healthy individuals exposed to low levels of cigarette smoke have a decrement in lung function and higher risk for lung disease compared to unexposed individuals. We hypothesized that healthy individuals exposed to low levels of tobacco smoke must have biologic changes in the small airwa...
ORGANISM(S): Homo sapiens 
2011-02-02 | E-GEOD-19667 | biostudies-arrayexpress
TranscriptomicsEvaluation of the amplicons for SNP typing (allele bias) and locus bias using Illumina 550-Duo BeadChip
Highly specific amplification of complex DNA pools without bias or template-independent products (TIPs) remains a challenge. We have developed a procedure using phi29 DNA polymerase and trehalose and optimized control of amplification to create micrograms of specific amplicons without TIPs from down...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-12732 | biostudies-arrayexpress
TranscriptomicsTranscriptional changes in dormant potato minitubers treated with 1-(alpha-ethylbenzy)-3-nitroquanidine
RNA was sequenced from commercially grown greenhouse minitubers treated with 10 ug of 1-(alpha-ethylbenzy)-3-nitroquanidine (NG) in DMSO and followed for four, and seven days post treatment. Control tubers were injected with DMSO alone. Sequence reads were mapped to the potato genome (PGSC_DM_v3_2.1...
ORGANISM(S): Solanum tuberosum 
2014-12-04 | E-MTAB-5038 | biostudies-arrayexpress
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