Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of rat chondrocytes treated with glucosamine exogenous glucosamine globally protects chondrocytes from the arthritogenic effects of IL-1beta
Glucosamine proved to be a potent, broad-spectrum inhibitor of IL-1beta. Of the 2,813 genes whose transcription was altered by IL-1beta stimulation (p<0.0001), glucosamine significantly blocked the response in 2,055 (~73%). Glucosamine fully protected the chondrocytes from IL-1-induced expression of...
ORGANISM(S): Rattus norvegicus 
2009-04-23 | E-GEOD-6119 | biostudies-arrayexpress
TranscriptomicsEffect of Sunitinib treatment withdrawal on Immunodeficient mice bearing MDA-MB231 tumors
Immunodeficient RAG1-/- mice bearing MDA-MB231-LUC+ tumors of 50-70 mm3 were daily administrated by gavage with vehicle (containing, 0.5% carboxymethylcellulose, 1.8 % NaCl, 0.4 % Tween-80, 0.9 %. benzyl alcohol, and ultrapure water adjusted to pH 6.0) or sunitinib (40mg/kg/day) for 30 days followed...
ORGANISM(S): Mus musculus 
2014-08-24 | E-GEOD-50795 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of imatinib-treated and untreated human Hematopoetic progenitors expressing the ETV6-PDGFRB oncogene
In order to investigate the mechanism whereby TEL-PDGF-beta (ETV6-PDGFRB) interferes with human hematopoietic progenitors proliferation and differentiation, we analyzed the gene expression response downstream this oncogene. CD34+ cells infected with lentivirus coding for TEL-PDGFRb were cultured for...
ORGANISM(S): Homo sapiens 
2012-04-09 | E-GEOD-28698 | biostudies-arrayexpress
TranscriptomicsRNA-seq of estrogen (E2) induced changes of mRNA expression in early pregnant Sus scrofa endometrium
Maternal exposure to estrogens can induce long-term adverse effects in the offspring. This may be mediated through alterations in the endometrium affecting embryo-maternal communication as early as the preimplantational phase. Thus, we analyzed the effects of gestational estradiol-17β (E2) exposure ...
ORGANISM(S): Sus scrofa 
2018-10-16 | E-MTAB-6242 | biostudies-arrayexpress
TranscriptomicsExpression and DNA methylation of colon cancer cell lines
This SuperSeries is composed of the following subset Series: GSE34077: Colon Cancer cell line YB5 untreated cells vs YB5 treated 24h with Depsipeptide at 20 nM GSE34427: DNA methylation analysis of Colon Cancer cell line SW48 Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-34429 | biostudies-arrayexpress
UnknownDo women with statin-related myalgias have low vitamin D levels?
Not available
S-EPMC4574117 | biostudies-literature
UnknownCo-stimulation of the fc receptor and interleukin-12 receptor on human natural killer cells leads to increased expression of cd25.
Not available
S-EPMC5749624 | biostudies-literature
TranscriptomicsDNA methylation analysis of Colon Cancer cell line SW48
We combined gene expression experiments in response to HDAC inhibitor Depsipeptide with DNA methylation level to assess gene reactivation arising from hypermethylated promoters. We did one experiment with 1 untreated and 1 treated batch of cells
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-34427 | biostudies-arrayexpress
TranscriptomicsMast cell microRNAs regulated by KIT signaling
Objective is to identify microRNAs regulated by KIT signaling in mast cells. miRNA profiles of murine bone marrow derived mast cells with and without SCF treatment were compared. In addition, miRNA profiles of the P815 mutant KIT cell line with and without the KIT inhibitor, imatinib, were compare...
ORGANISM(S): Mus musculus 
2011-01-25 | E-GEOD-26783 | biostudies-arrayexpress
UnknownAdding Celecoxib With or Without Zoledronic Acid for Hormone-Naive Prostate Cancer: Long-Term Survival Results From an Adaptive, Multiarm, Multistage, Platform, Randomized Controlled Trial.
Not available
S-EPMC5455701 | biostudies-literature
Sort   by:  
 Page size