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TranscriptomicsConsequences of GATA1 expression in Gata1- G1ME Murine Megakaryocyte/Erythrocyte Progenitor Cell Line
G1ME cells are GATA1-deficient murine bipotential megakaryocyte/erythrocyte progenitor cells derived from Gata1-negative murine ES cells. In order to assess the impact of GATA1 on gene regulation and cell differentiation, an expression construct was used to transiently produce high levels of GATA1....
ORGANISM(S): Mus musculus 
2009-06-10 | E-GEOD-14980 | biostudies-arrayexpress
UnknownGenome-Wide DNA Methylation Analysis Reveals Epigenetic Dysregulation of MicroRNA-34A in TP53-Associated Cancer Susceptibility.
Not available
S-EPMC6366343 | biostudies-literature
UnknownTP53 Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children.
Not available
S-EPMC5815403 | biostudies-literature
GenomicsGermline Aberrations of PAX5 Cause Susceptibility to pre-B cell Acute Lymphoblastic Leukemia
A novel heterozygous germline variant, c.547G>A (p.Gly183Ser), in the paired box protein encoding gene, PAX5, was found to segregate with disease in two unrelated kindreds with autosomal dominant pre-B cell acute lymphoblastic leukemia (ALL). Leukemic cells from both families exhibited 9p deletion, ...
EGAS00001000447 | EGA
GenomicsGEenetic landscape of hypodiploid acute lymphoblastic leukemia
Hypodiploid acute lymphoblastic leukemia (ALL) is an aggressive leukemia characterized by aneuploidy and poor outcome. The genetic basis of hypodiploid ALL is unknown. Here, using complementary genome-wide profiling approaches, we show that hypodiploid ALL comprises two subtypes that differ in the s...
EGAS00001000380 | EGA
GenomicsPCGP BALL-PAX5 WES - samples
Description not provided
EGAD00001001056 | EGA
GenomicsPCGP INF WES - samples
DATA FILES FOR PCGP SJINF WES
EGAD00001001245 | EGA
GenomicsPCGP HYPO - samples
Hypodiploid acute lymphoblastic leukemia whole genome sequencing
EGAD00001000260 | EGA
GenomicsPCGP INF RNASeq - samples
DATA FILES FOR SJINF RNASeq
EGAD00001001098 | EGA
GenomicsPCGP PHALL - samples
DATA FILES FOR SJPHALL
EGAD00001000163 | EGA
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