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ProteomicsProteomic profiling identifies muscle-invasive bladder cancers with distinct biology and responses to platinum-based chemotherapy
Platinum-based neoadjuvant chemotherapy (NAC) prior to radical cystectomy is the preferred treatment for muscle-invasive bladder cancer (MIBC) despite modest survival benefit and significant associated toxicities. Here, we profiled the global proteome of MIBC tumours pre- and post-NAC treatment usin...
ORGANISM(S): Homo sapiens (Human) 
2025-02-11 | PXD049435 | Pride
Bladder cancer Mibc 
TranscriptomicsMeta-analysis of Clear Cell Renal Cell Carcinoma Gene Expression Defines a Variant Subgroup and Identifies Gender Influences on Tumor Biology
Clear cell renal cell carcinoma comprises two dominant subtypes, ccA and ccB, with gender disparity providing additional disease information. A third minor subgroup has distinct expression profiles consistent with von Hippel-Lindau wild type status and displays variant histology features. 44 new tum...
ORGANISM(S): Homo sapiens 
2011-11-05 | E-GEOD-33093 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae during prolonged maltose limited cultivation
Prolonged cultivation (>25 generations) of Saccharomyces cerevisiae in aerobic, maltose-limited chemostat cultures led to profound physiological changes. Maltose hypersensitivity was observed when cells from prolonged cultivations were suddenly exposed to excess maltose. This substrate hypersensitiv...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-8897 | biostudies-arrayexpress
TranscriptomicsSalmonella under environmental stress
The aim of this study is to investigate the transcriptional response of S. Typhimurium to heat, osmotic, oxidative and acid stress under anoxic and oxic conditions and to non-stressed anoxic conditions.
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2013-11-11 | E-MTAB-1804 | biostudies-arrayexpress
GenomicsAboriginal Australia Genome Consortium
Data Access Committee EGAC00001000465
EGAC00001000465 | EGA
Genomicsena-DATASET-UNIBE-07-04-2016-07:41:15:505-596 - samples
Mapped data (bam files) for high-throughput whole genome sequence data for 83 modern Aboriginal Australians
EGAD00001002001 | EGA
Genomics37a30206-29b3-47a0-90c4-eee326fe5b8b - samples
Genotype calls for 83 Aboriginal Australian genomes split by chromosomes. In short, genotypes were called individually with samtools. They were subsequently filtered with thresholds related to sequencing depth, location of variants, sequencing error, and strand bias. Once combined, the genotypes wer...
EGAD00001004155 | EGA
GenomicsRFMix
This dataset contains the per-chromosome RFMix input and output files for the local ancestry inference of 59 Aboriginal Australian genomes as reported in Malaspinas et al., 2016. Local ancestry was inferred assuming four mixing ancestral populations represented by: Europeans (27 individuals), Asians...
EGAD00010001575 | EGA
GenomicsMT alignment
Alignement including 83 MT AA sequences and 2 reference sequences, rCRS and RSRS
EGAD00010001574 | EGA
GenomicsY chromosome alignment
Variations on the Y chromosome from 44 samples
EGAD00010001573 | EGA
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