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GenomicsGlutamine methylation on Histone H2A is an RNA Polymerase I dedicated modification
Nucleosomes are decorated with numerous post-translational modifications capable of influencing many DNA processes. Here, we describe a new class of modification, methylation of glutamine, occurring on yeast histone H2A at position 105 (Q105) and human H2A at Q104. We identify Nop1 as the methyltran...
ORGANISM(S): Saccharomyces cerevisiae 
2014-01-21 | E-MTAB-1447 | biostudies-arrayexpress
TranscriptomicsHuman s.c adipose tissue gene expression during diet-induced weight loss
Obesity has considerable effects on morbidity and mortality and the prevalence of obesity has been increasing rapidly worldwide during the past two decades. Even if obesity affects the entire individual, adipose tissue play a central role in the development of obesity. Expression profiling of adipos...
ORGANISM(S): Homo sapiens 
2013-01-22 | E-GEOD-35710 | biostudies-arrayexpress
TranscriptomicsHuman subcutaneous adipose tissue gene expression (SOS Sib-pair study, offspring cohort)
Obesity has considerable effects on morbidity and mortality, and the prevalence of obesity has been increasing rapidly worldwide during the past two decades. Even if obesity affects the entire individual, adipose tissue plays a central role in the development of obesity. Expression profiling of adip...
ORGANISM(S): Homo sapiens 
2013-01-22 | E-GEOD-27916 | biostudies-arrayexpress
UnknownA Selective Sweep on a Deleterious Mutation in CPT1A in Arctic Populations.
Not available
S-EPMC4225582 | biostudies-literature
UnknownRomidepsin for the treatment of relapsed/refractory peripheral T-cell lymphoma: pivotal study update demonstrates durable responses.
Not available
S-EPMC4016573 | biostudies-literature
UnknownRisks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants.
Not available
S-EPMC10170303 | biostudies-literature
UnknownCigarette smoking is associated with adverse survival among women with ovarian cancer: Results from a pooled analysis of 19 studies.
Not available
S-EPMC5489656 | biostudies-literature
Unknown9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium.
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S-EPMC3772723 | biostudies-literature
UnknownBody mass index and breast cancer survival: a Mendelian randomization analysis.
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S-EPMC5837506 | biostudies-literature
UnknownGenetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium.
Not available
S-EPMC4698282 | biostudies-literature
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