Sort   by:  
 Page size 
ProteomicsDepletion of the RNA-binding protein PURA triggers changes in posttranscriptional gene regulation and loss of P-bodies
The RNA-binding protein PURA has been implicated in the rare, monogenetic, neurodevelopmental disorder PURA Syndrome. PURA binds both DNA and RNA and has been associated with various cellular functions. Only little is known about its main cellular functions and the molecular pathways affected upon P...
ORGANISM(S): Homo sapiens (Human) 
2022-12-19 | PXD030266 | Pride
Pura 
TranscriptomicsFunctional dissection of the Paired domain of Pax6 – distinct roles of subdomains in neurogenesis and proliferation
The transcription factor Pax6 acts as a key developmental regulator in various organs. In the developing brain Pax6 regulates patterning, neurogenesis and proliferation, but how these diverse effects are mediated at the molecular level is not well understood. As Pax6 regulates forebrain development ...
ORGANISM(S): Mus musculus 
2013-03-19 | E-GEOD-35260 | biostudies-arrayexpress
ProteomicsYeast phosphofructokinase subunit 2 has ATP-dependent RNA unwinding activity and modulates cell cycle progression
Phosphofructokinase (PFK) is a rate-limiting glycolytic enzyme that also possesses an unexplored polyadenylated RNA binding activity. Here, we show that the two PFK subunits, Pfk1 and Pfk2, in budding yeast bind a large number of mRNAs in cells, including ones coding for proteins involved in regulat...
ORGANISM(S): Saccharomycetales (ncbitaxon:4892) 
2024-12-04 | MSV000096586 | MassIVE
Sort   by:  
 Page size