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TranscriptomicsmRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer
The intention was to detect genes that are determining trastuzumab efficiency in HER2-positive breast cancer cell lines with different resistance phenotypes. While BT474 should be sensitive to the drug treatment, HCC1954 is expected to be resistant due to a PI3K mutation. The cell line BTR50 has bee...
ORGANISM(S): Homo sapiens 
2015-04-21 | E-GEOD-55005 | biostudies-arrayexpress
ProteomicsReverse phase protein array based protein profiling of breast cancer specimens
Expression levels of proteins and phosphoproteins, covering major cancer signaling pathways with a special focus on breast cancer biology, were obtained for a series of 109 breast cancer tumor specimens with positive estrogen receptor status. Tumor specimens from patients diagnosed with primary inva...
ORGANISM(S): Homo sapiens 
2014-02-18 | E-GEOD-47066 | biostudies-arrayexpress
ProteomicsReverse phase protein array based protein profiling of breast cancer specimens (2)
Expression levels of proteins and phosphoproteins, covering major cancer signaling pathways with a special focus on breast cancer biology, were obtained for a series of 164 breast cancer tumor specimens with positive estrogen receptor status. Tumor specimens from patients diagnosed with primary inva...
ORGANISM(S): Homo sapiens 
2014-02-18 | E-GEOD-50861 | biostudies-arrayexpress
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