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TranscriptomicsTranscription profiling of mouse nephron to assess circadian rhythms
Renal excretion of water and major electrolytes exhibits a significant circadian rhythm. This functional periodicity is believed to result, at least in part, from circadian changes in secretion/reabsorption capacities of the distal nephron and collecting ducts. Here, we studied the molecular mechani...
ORGANISM(S): Mus musculus 
2009-10-30 | E-GEOD-17739 | biostudies-arrayexpress
TranscriptomicsMice lacking circadian transcriptional activator Clock exhibit dramatic changes in renal excretory rhythms
Recent evidence suggest that the circadian timing system plays an important role in the control of renal function and maintaining blood pressure. Here, we analyzed circadian rhythms of urinary excretion of sodium and potassium in wild-type mice and mice lacking circadian transcriptional activator cl...
ORGANISM(S): Mus musculus 
2012-04-29 | E-GEOD-27366 | biostudies-arrayexpress
TranscriptomicsTargeted deletion of circadian clock gene Arntl in the nephron results in dysregulation of diverse metabolic pathways
The circadian clock controls a wide variety of metabolic and homeostatic processes in a number of tissues, including the kidney. However, the role of the renal circadian clocks remains largely unknown. To address this question we performed transcriptomic analysis in mice with inducible and condition...
ORGANISM(S): Mus musculus 
2016-06-01 | E-GEOD-76838 | biostudies-arrayexpress
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