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TranscriptomicsHuman induced pluripotent stem cell-technology to study the effects of human cytomegalovirus infection on neural differentiation
Congenital human cytomegalovirus (HCMV) infection is one of the leading prenatal causes of mental retardation and congenital deformities world-wide. Access to cultured human neuronal lineages, necessary to understand the species specific pathogenic effects of HCMV has been limited by difficulties i...
ORGANISM(S): Homo sapiens 
2013-01-04 | E-GEOD-35295 | biostudies-arrayexpress
TranscriptomicsHuman cellular models for Herpes Simplex Virus, type 1 (HSV-1) using induced pluripotent stem cell derived neuronal lineages
Herpes simplex virus type 1 (HSV-1) is a 152 Kb double stranded DNA alpha-herpesvirus, which establishes long life latent infection in sensory neurons. Most of our knowledge regarding HSV-1 latency comes from in vivo studies using small animal models, mainly rodents and rabbits, which are not natura...
ORGANISM(S): Homo sapiens 
2014-05-02 | E-GEOD-46041 | biostudies-arrayexpress
TranscriptomicsInduced pluripotent stem cell derived neuronallineages as human cellular models for Herpes Simplex Virus, type 1 (HSV-1) infections
Herpes simplex virus type 1 (HSV-1) is a 152 Kb double stranded DNA alpha-herpesvirus, which establishes long life latent infection in sensory neurons. Most of our knowledge regarding HSV-1 latency comes from in vivo studies using small animal models, mainly rodents and rabbits, which are not natura...
ORGANISM(S): Homo sapiens 
2014-05-02 | E-GEOD-46042 | biostudies-arrayexpress
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