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TranscriptomicsTranscription profiling of mouse NIH3T3 cell line cultured with and withput FGF and treated with the MEK Inhibitor U0126 at 3 time points before FGF addition reveals ERK-dependent downregulated genes have the ability to block S phase entry
The ERK family of MAP kinase plays a critical role in growth factor-stimulated cell cycle progression from G0/G1 to S phase. But, how sustained activation of ERK promotes G1 progression has remained unclear. Here, our systematic analysis on the temporal program of ERK-dependent gene expression shows...
ORGANISM(S): Mus musculus 
2007-11-24 | E-GEOD-4739 | biostudies-arrayexpress
Proteomics2H-Thiopyran-2-Thione Sulfine, a Compound For Converting H2S to HSOH/H2S2 and Increasing Intracellular Sulfane Sulfur Levels
Reactive sulfane sulfur species such as persulfides (RSSH) and H2S2 are important redox regulators and closely linked to H2S signaling. However, the study of these species is still challenging due to their instability, high reactivity, and the lack of suitable donors to produce these species. Herein...
ORGANISM(S): Oryctolagus Cuniculus (ncbitaxon:9986) 
2024-02-07 | MSV000094034 | MassIVE
UnknownDescription and biology of two new species of Neotropical Liriomyza Mik (Diptera, Agromyzidae), mining leaves of Bocconia (Papaveraceae).
Not available
S-EPMC3904121 | biostudies-literature
TranscriptomicsHCT 116 cells expressing Fucci (fluorescent ubiquitination-based cell cycle indicator); G1 phase vs. S/G2/M phase
Fucci-expressing HCT116 were inoculated into subcutaneous tissue or cecum of NOD/SCID mice. Four weeks after inoculation, Fucci green (mAG; S/G2/M) and red (mKO2;G1) expressing cells were isolated from implanted tumors by FACSAria sorting (BD, Biosciences). Comparative analyses among green and red c...
ORGANISM(S): Homo sapiens 
2014-01-09 | E-GEOD-34940 | biostudies-arrayexpress
UnknownValidation of Male Pontella spinipes Giesbrecht, 1889 (Copepoda: Calanoida: Pontellidae) Based on Morphological and Mitochondrial COI Gene Sequence Analysis.
Not available
S-EPMC6517714 | biostudies-literature
UnknownAntibacterial coating of tooth surface with ion-releasing pre-reacted glass-ionomer (S-PRG) nanofillers.
Not available
S-EPMC7889979 | biostudies-literature
UnknownHeterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y2 receptor stimulation through S-nitrosylation of NF-kappaB.
Not available
S-EPMC3080971 | biostudies-literature
ProteomicsPolysulfur-based bulking of dynamin-related protein 1 prevents ischemic sulfide catabolism and heart failure
The presence of redox-active molecules containing catenated sulfur atoms (supersulfide) in living organisms has led to a review of the concepts of redox biology and its translational strategy. Glutathione (GSH) is the body’s primary detoxifier and antioxidant, and its oxidized form (GSSG) has been c...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-11-16 | PXD053562 | Pride
Mitochondria Glutathionylation Heart failure Drp1 Supersulfide catabolism 
UnknownHistological complete response in a patient with advanced biliary tract cancer treated by gemcitabine/cisplatin/S-1 combination chemotherapy: A case report.
Not available
S-EPMC5228213 | biostudies-literature
TranscriptomicsA New Oxidative Sensing and Regulation Pathway Mediated by the MgrA Homologue SarZ in Staphylococcus aureus
The S. aureus transcriptome was assessed for strains Newman (wild type) and Newman (sarZ) during both exponential (2hr) and early stationary (5hr) cell growth. The S. aureus transcriptome was assessed for strains Newman (wild type) and Newman (sarZ) during both exponential (2hr) and early stationary...
ORGANISM(S): Staphylococcus aureus 
2010-05-15 | E-GEOD-13138 | biostudies-arrayexpress
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