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MetabolomicsWhat CHO is made of: Variations in the biomass composition of Chinese hamster ovary cell lines

Background: Cell line specific, genome-scale metabolic models enable rigorous and systematic in silico investigation of cellular metabolism. Such models have recently become available for Chinese hamster ovary (CHO) too. However, a key ingredient, namely an experimentally validat...

2020-07-13 | MTBLS1210 | MetaboLights
TranscriptomicsComparative genomic hybridization of human nasal NK/T-cell Lymphoma (8 tumor samples, 2 cell lines)
A ﾑCartes dﾒIdentite des Tumeursﾒ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net ) | Human genome-wide CIT-aCGH-V6-4.4K : 8 NKTCL biopsies, 2 NKTCL cell lines. Biopsies and cell lines of NK/T-cell lymphoma, nasal-type (NKTCL) were subject to combine...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-TABM-791 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing and single-cell CRISPR screens of interacting natural killer and blood cancer cells
To profile the cell states of interacting natural killer (NK) cells and blood cancer cells, we cultured 26 different cell lines representing diverse hematologic neoplasms either alone or with NK cells derived from three healthy human donors. After 24 h co-culture, we labeled the cells from each mono...
ORGANISM(S): Homo sapiens 
2023-07-24 | E-MTAB-13204 | biostudies-arrayexpress
TranscriptomicsIdentification of FOXO3 and PRDM1 as tumor suppressor gene candidates in NK cell neoplasms by the combination of genomic and functional analyses -CGH
Array-CGH analysis of NK cell neoplasm (clinical samples + cell lines)
ORGANISM(S): Homo sapiens 
2011-06-11 | E-MEXP-3002 | biostudies-arrayexpress
TranscriptomicsmiRNA expression in NK cells
The goal of this study is to characterize the miRNA expression in both freshly isolated and cultured NK cells from both mice and humans. (2 samples from mouse cells (naive and cultured), 2 from human cells (naïve and cell line), 4 samples total) At this point, this experiment involves one replicate ...
ORGANISM(S): Mus musculus 
2011-02-23 | E-GEOD-27249 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human non anaplastic T-cell lymphoma biopsies and cell lines
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net) | Affymetrix HG-U133 Plus 2.0 : 7 NKTCL biopsies, 2 NKTCL cell lines (SNK6, SNT8), 16 PTCL NOS biopsies, 2 NK cells samples | Biopsies and cell lines of NK/T-cell lymphoma, na...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-TABM-702 | biostudies-arrayexpress
TranscriptomicsRNA-seq of NK-92 cell line upon BET inhibitor treatment (OTX-015)
Identification of the mechanisms through which BET inhibitor (OTX-015) stimulates natural killer (NK) activation. RNA-seq was performed comparing vehicle- (DMSO) to OTX-015-treated NK-92 cell line.
ORGANISM(S): Homo sapiens 
2024-01-26 | E-MTAB-12853 | biostudies-arrayexpress
TranscriptomicsComprehensive gene expression profiles of NK cell neoplasms identify vorinostat as an effective drug candidate
Transcriptional profiling of NK cell lines (NKL & NKYS) with DMSO or vorinostat
ORGANISM(S): Homo sapiens 
2013-01-24 | E-MTAB-1410 | biostudies-arrayexpress
TranscriptomicsMicroRNA-15/16 Antagonizes c-Myb to Control Natural Killer Cell Maturation (c-Myb overexpression)
NK cells develop in the bone marrow and complete their maturation in peripheral organs, but the molecular events controlling maturation are incompletely understood. Utilizing an NK cell-specific miR-15/16 deficient genetic model (15aKO), we identified a critical role for miR-15/16 family microRNAs i...
ORGANISM(S): Mus musculus 
2015-09-03 | E-GEOD-58268 | biostudies-arrayexpress
TranscriptomicsMicroRNA microarray analysis in nasal NK/T-cell lymphoma cell lines
Gene expression profiling of 1,211 microRNAs in nasal NK/T-cell lymphoma cell lines Gene expression profiling of 1,211 microRNAs in three nasal NK/T-cell lymphoma cell lines, EBV-negative NK-cell line and normal NK cells
ORGANISM(S): Homo sapiens 
2014-02-01 | E-GEOD-43958 | biostudies-arrayexpress
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