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TranscriptomicsA High Resolution Profile of NMD Substrates in Yeast
We report a high resolution catalouge of NMD substrates using RNA-Seq. We discovered several hundred new substrates for NMD. Using published ribosome footprint profiling data, we measured ribosome densities of normal-looking NMD substrates and non-NMD substrates. NMD substrates exhibited a striking ...
ORGANISM(S): Saccharomyces cerevisiae 
2016-12-02 | GSE86428 | GEO
TranscriptomicsGenome-wide analysis of cellular NMD substrates that regulated by Upf1, PNRC2 or CTIF in HeLa cell
The first round of translation occurs on mRNAs bound by nuclear cap-binding complex (CBC), which is composed of nuclear cap-binding protein (CBP) 80 and 20. During this round of translation, aberrant mRNAs are recognized and downregulated in abundance by nonsense-mediated mRNA decay (NMD), which is ...
ORGANISM(S): Homo sapiens 
2012-07-22 | E-GEOD-37538 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of cellular SMD or NMD substrates that regulated by Upf1 or PNRC2 in HeLa cell
Analysis of cellular SMD or NMD substrates that regulated by Upf1 and/or PNRC2 in HeLa cell. The hypothesis tested in the present study was that endogenous SMD or NMD substrates may co-regulated by Upf1 and PNRC2. Results provide important information that vast range of cellular SMD or NMD substrate...
ORGANISM(S): Homo sapiens 
2012-02-28 | GSE26781 | GEO
TranscriptomicsGenome-wide analysis of miRNA-targeted cellular NMD substrates in HeLa cell
Analysis of miRNA-targeted cellular NMD substrates in HeLa cell. The hypothesis tested in the present study was that endogenous NMD substrates containing long 3' untranslated region may targeted for miRNA. Results provide important information expanding the roles of miRISC in the posttranscriptional...
ORGANISM(S): Homo sapiens 
2010-03-08 | GSE16170 | GEO
TranscriptomicsGenome-wide analysis of cellular NMD substrates that regulated by Upf1, PNRC2 or CTIF in HeLa cell
The first round of translation occurs on mRNAs bound by nuclear cap-binding complex (CBC), which is composed of nuclear cap-binding protein (CBP) 80 and 20. During this round of translation, aberrant mRNAs are recognized and downregulated in abundance by nonsense-mediated mRNA decay (NMD), which is ...
ORGANISM(S): Homo sapiens 
2012-07-23 | GSE37538 | GEO
GenomicsSaccharomyces cerevisiae
A High Resolution Profile of NMD Substrates in Yeast
PRJNA341846 | ENA
TranscriptomicsGenome-wide analysis of miRNA-targeted cellular NMD substrates in HeLa cell
Analysis of miRNA-targeted cellular NMD substrates in HeLa cell. The hypothesis tested in the present study was that endogenous NMD substrates containing long 3' untranslated region may targeted for miRNA. Results provide important information expanding the roles of miRISC in the posttranscriptional...
ORGANISM(S): Homo sapiens 
2010-04-09 | E-GEOD-16170 | biostudies-arrayexpress
UnknownAssociation of yeast Upf1p with direct substrates of the NMD pathway.
Not available
S-EPMC2409234 | biostudies-literature
TranscriptomicsGenome-wide analysis of cellular SMD or NMD substrates that regulated by Upf1 or PNRC2 in HeLa cell
Analysis of cellular SMD or NMD substrates that regulated by Upf1 and/or PNRC2 in HeLa cell. The hypothesis tested in the present study was that endogenous SMD or NMD substrates may co-regulated by Upf1 and PNRC2. Results provide important information that vast range of cellular SMD or NMD substrate...
ORGANISM(S): Homo sapiens 
2012-02-28 | E-GEOD-26781 | biostudies-arrayexpress
GenomicsCRISPR screen for NMD regulators
CRISPR screen for NMD regulators
PRJNA602918 | ENA
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