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GenomicsNuclear NAD+-biosynthetic enzyme NMNAT1 facilitates survival of developing retinal neurons
Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates survival of developing retinal neurons
PRJNA738469 | ENA
GenomicsTranscriptomic effects of nicotinamide nucleotide adenylyltransferase 1 (NMNAT1) deletion on human AML cells
Transcriptomic effects of nicotinamide nucleotide adenylyltransferase 1 (NMNAT1) deletion on human AML cells
PRJNA720103 | ENA
TranscriptomicsHepatic NMNAT1 is required to defend against alcohol-associated fatty liver disease
Nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1), an NAD+ synthetase in Preiss-Handler and salvage pathways, governs nuclear NAD+ homeostasis. This study investigated the role of NMNAT1 on alcohol-associated liver disease (ALD). Decreased NMNAT1 expression and activity were observed in the...
ORGANISM(S): Mus musculus 
2025-05-25 | GSE297696 | GEO
UnknownExpression of NMNAT1 in the photoreceptors is sufficient to prevent NMNAT1-associated retinal degeneration.
Not available
S-EPMC10193288 | biostudies-literature
TranscriptomicsExpression analysis upon NMNAT1 knockdown in MCF-7 cells
NMNAT1 is a nuclear enzyme in the mammalian NAD+ salvage pathway. Expression microarray analysis was used to study the effect of NMNAT1 knockdown on gene expression in MCF-7 breast cancer cells.
ORGANISM(S): Homo sapiens 
2009-05-28 | GSE13458 | GEO
GenomicsComprehensive gene expression profile of mouse explant retinas expressing shNmnat1, shNmnat2, Nmnat1 and Nmnat2
Comprehensive gene expression profile of mouse explant retinas expressing shNmnat1, shNmnat2, Nmnat1 and Nmnat2
PRJNA809347 | ENA
TranscriptomicsTranscriptomic effects of nicotinamide nucleotide adenylyltransferase 1 (NMNAT1) deletion on human AML cells
Through integration of whole genome CRISPR screening and pan-cancer genetic dependency mapping, we identified nicotinamide phosphoribosyltransferase (NAMPT) and nicotinamide nucleotide adenylyltransferase 1 (NMNAT1) as acute myeloid leukemia (AML) dependencies governing NAD+ biosynthesis. While both...
ORGANISM(S): Homo sapiens 
2021-07-28 | GSE171565 | GEO
UnknownNmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7.
Not available
S-EPMC4664474 | biostudies-literature
UnknownNMNAT1 mutations cause Leber congenital amaurosis.
Not available
S-EPMC3454532 | biostudies-literature
UnknownCharacterization of Leber Congenital Amaurosis-associated NMNAT1 Mutants.
Not available
S-EPMC4498062 | biostudies-literature
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