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GenomicsDefining codon-mediated mRNA decay and No-go decay in zebrafish embryos
Defining codon-mediated mRNA decay and No-go decay in zebrafish embryos
PRJNA551383 | ENA
TranscriptomicsDefining codon-mediated mRNA decay and No-go decay in zebrafish embryos
The control of mRNA stability plays a central role in regulating gene expression patterns. While much is known about the roles of 5´ and 3´ untranslated regions in the mRNA stability control, the impact of protein-coding sequences on mRNA stability had been obscure. Recently, several groups reported...
ORGANISM(S): Danio rerio 
2020-05-05 | GSE133392 | GEO
GenomicsYeast elongation factor homolog New1 protects a subset of mRNAs from degradation by no-go decay
Yeast elongation factor homolog New1 protects a subset of mRNAs from degradation by no-go decay
PRJNA1149092 | ENA
GenomicsCharacterization of ribosome stalling and no-go mRNA decay stimulated by the Fragile X protein, FMRP
Characterization of ribosome stalling and no-go mRNA decay stimulated by the Fragile X protein, FMRP
PRJNA1071088 | ENA
UnknownmRNA levels can be reduced by antisense oligonucleotides via no-go decay pathway.
Not available
S-EPMC6649848 | biostudies-literature
UnknownThe endonuclease Cue2 cleaves mRNAs at stalled ribosomes during No Go Decay.
Not available
S-EPMC6598757 | biostudies-literature
UnknownRibosome Collision Is Critical for Quality Control during No-Go Decay.
Not available
S-EPMC5659757 | biostudies-literature
OtherYeast elongation factor homolog New1 protects a subset of mRNAs from degradation by no-go decay
New1 is a homolog of fungal translation elongation factor 3 (eEF3) inSaccharomyces cerevisiae. Its absence has previously been described to lead to cold sensitivity, ribosome biogenesis defects, and ribosomal queues upstream of Stop codons on selected mRNAs. Here, we find that, especially in cold co...
ORGANISM(S): Saccharomyces cerevisiae 
2024-11-26 | GSE275093 | GEO
UnknownRibosome Collisions Result in +1 Frameshifting in the Absence of No-Go Decay.
Not available
S-EPMC6701860 | biostudies-literature
UnknownDom34:Hbs1 promotes subunit dissociation and peptidyl-tRNA drop-off to initiate no-go decay.
Not available
S-EPMC4022135 | biostudies-literature
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