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Zebrafish embryos microinjected with ptGFP1 (control group) or ptGFP1-NOD1 (NOD1 group)
NOD1 activity attenuates obesity in mice fed a high fat diet
HEK293T cells were transiently transfected with NOD1-FLAG and HA-SspH2 WT/HA-SspH2 C580/empty vector. Following anti-FLAG automated immunoprecipitation and in-gel trypsin digestion, fractionated samples were injected onto LC-MS/MS. Quantitation was performed on diglycyl-lysine sites on NOD1, on iden...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-06-24 | MSV000087700 | MassIVE
HEK293T cells were transiently transfected with NOD1-FLAG, HA-SspH2 WT/HA-SspH2 C580/empty vector, and Myc-Ubiquitin. Following anti-FLAG automated immunoprecipitation and in-gel trypsin digestion, fractionated samples were injected onto LC-MS/MS. Quantitation was performed on diglycyl-lysine sites ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-06-23 | MSV000087693 | MassIVE
Microbial-ligand independent regulation of lymphpoiesis by NOD1
Transcriptional profiling of zebrafish embryos comparing control group microinjected with empty plasmid with NOD1 group microinjected with ptGFP1-NOD1 plasmid.
ORGANISM(S): Danio rerio 
2018-06-22 | GSE116109 | GEO
This is an investigation of whole genome gene expression level in tissues of mice stimulated by LPS, FK565 or LPS + FK565 in vivo and ex vivo. We show that parenteral administration of a pure synthetic Nod1 ligand, FK565, induces site-specific vascular inflammation in mice, which is prominent in aor...
ORGANISM(S): Mus musculus 
BCR ligand-engaged B cells upregulate Nod1 during development. Most mature B cells have up-regulated Nod1 and are sensitive to Nod1 signaling, which increases survival upon exposure to microbial products, as a positive outcome of BCR-engaged mature B cells.
ORGANISM(S): Mus musculus 
2017-09-03 | GSE101318 | GEO
METTL3 Regulates LPS-Induced Inflammatory Response via the NOD1 Signaling Pathway
Aberrant differentiation of progenitor cells in the hematopoietic system is known to severely impact host immune responsiveness. Here we demonstrate that NOD1, a cytosolic innate sensor of bacterial peptidoglycan, also functions in murine hematopoietic cells as a major regulator of both the generati...
ORGANISM(S): Mus musculus 
2023-10-25 | GSE236485 | GEO
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