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Background: Mice lacking either T-cell intracellular antigen 1 (TIA1) or TIA1-related/like protein (TIAR/TIAL1) show high rates of embryonic lethality, suggesting a relevant role for these proteins during embryonic development. However, intrinsic molecular and cellular consequences of either TIA1 or...
ORGANISM(S): Mus musculus 
The project analyses non-collagenous proteins (NCP's) present in rat bones of various age and sex to determine the various changes that take place in the NCP's with regard to age and sex
ORGANISM(S): Rattus rattus (Black rat) Rattus norvegicus (Rat) 
2023-07-24 | PXD022055 | Pride
Individual nucleotide resolution UV-crosslinking and immunoprecipitation (iCLIP) and individual nucleotide resolution UV-crosslinking and affinity purification (iCLAP) were used to identify the global RNA binding sites for TIA1 and TIAL1 proteins. HeLa cells were UV crosslinked before lysing and dig...
ORGANISM(S): Homo sapiens 
Isotope analyses are some of the most common analytical methods applied to ancient bone, aiding the interpretation of past diets and chronology. For this, the evaluation of “collagen” yield is a routine step that allows for the selection of the specimens that are adequate for subsequent analyses, an...
ORGANISM(S): Bos taurus (Bovine) Cervus elaphus (Red deer) Homo sapiens (Human) Equus caballus (Horse) 
2021-02-08 | PXD020516 | Pride
The knock down of T-cell intracellular antigen (TIA) proteins enhances the acquisition of aberrant cellular phenotypes promoting uncontrolled cell and tumor growth. Hereby, we report that inducible expression of either TIA1 or TIAR in human embryonic kidney (HEK293) cells represses cell proliferatio...
ORGANISM(S): Homo sapiens 
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