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TranscriptomicsReplacing skeletal muscle alpha-actin with cardiac actin in mouse skeletal muscle
Skeletal muscle actin mice (Crawford et al., (2002) Mol Cell Biol 22, 5587) were crossed with cardiac actin transgenic mice (termed "ACTC^Coco" or "Coco" for short), to produce mice that had cardiac actin instead of skeletal muscle actin in their skeletal muscles (termed "AC...
ORGANISM(S): Mus musculus 
2009-05-24 | E-GEOD-12882 | biostudies-arrayexpress
ProteomicsPurification of Human β and γ Actin from Budding Yeast
To facilitate biochemical studies of human cytoplasmic actins, Saccharomyces cerevisiaestrains were developed that express either human β-actin or γ-actin as their sole actin. Actins purified from these strains have biochemical properties similar to mammalian skeletal muscle α-actin, but display di...
ORGANISM(S): Oryctolagus sp. 'Rabbit_OD' Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2023-04-24 | PXD040174 | Pride
Β-actin Cytoplasmic actin Non-muscle actin Γ-actin 
TranscriptomicsA putative network of actin-associated cytoskeletal proteins in glomerular podocytes defined by co-purified mRNAs
Identification of a putative network of actin-associated cytoskeletal proteins in glomerular podocytes defined by co-purified mRNAs. An experimental purification in which a presumed RNA binding protein was used for an RNA immunoprecipitation and microarray analysis (RIP-CHIP). Total cell extracts w...
ORGANISM(S): Mus musculus 
2009-08-01 | E-GEOD-16942 | biostudies-arrayexpress
ProteomicsDysregulation of Non-Muscle Myosin IIA Assembly and Phosphorylation in S100A4 Null Mouse Lens
Non-muscle myosin IIA (NMIIA), a motor protein plays a critical role in regulating cell morphology, adhesion, migration, contractility, and mechanotransduction across various tissues, including the ocular lens. S100A4, a known NMIIA-interacting protein, is abundantly expressed in lens fibers and sho...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-29 | PXD071603 | Pride
Mouse Actin cytoskeleton Cataract S1004a Myosin iia Lens 
UnknownTumor promotion by γ and suppression by β non-muscle actin isoforms.
Not available
S-EPMC4546487 | biostudies-literature
UnknownThe non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies.
Not available
S-EPMC8411111 | biostudies-literature
UnknownThe non-muscle actinopathy-associated mutation E334Q in cytoskeletal γ-actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins.
Not available
S-EPMC10942649 | biostudies-literature
TranscriptomicsTranscriptional profiling by array of human head and neck squamous cell carcinoma to study the correlation between galectin-1 upregulation and the presence of SMA positive cancer-associated fibroblasts
In this study, we set the presence of smooth muscle actin (SMA)-positive cancer-associated fibroblasts (CAFs) in relation to galectin-1 and its in vivo competitor (galectin-3). In squamous cell carcinomas of head and neck, upregulation of galectin-1 presence is highly significantly correlated to pre...
ORGANISM(S): Homo sapiens 
2012-11-01 | E-MTAB-850 | biostudies-arrayexpress
UnknownEffect of Load on Non-Muscle Myosin 2 Paralog Filaments in a Biomimetic Contractile Actin Array.
Not available
S-EPMC12802541 | biostudies-literature
UnknownIdentification of an FHL1 protein complex containing gamma-actin and non-muscle myosin IIB by analysis of protein-protein interactions.
Not available
S-EPMC3827166 | biostudies-literature
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