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MetabolomicsSystematic analyses of lipid mobilization by human lipid transfer proteins

Lipid transfer proteins (LTPs) maintain the specialised lipid compositions of biological membranes, and many are associated with disease. In eukaryotes, they support organellar functions by transporting lipids between compartmentalised metabolic pathways. However, for the majority of the hundreds...

2025-11-14 | MTBLS9567 | MetaboLights
MetabolomicsMembrane lipid as cofactor of cargo uptake and release by box-like lipid transfer proteins
Lipid transfer proteins (LTPs) shuttle their cargo lipids between cellular membranes. LTPs facilitate the costly extraction of a lipid from a donor membrane, and its delivery into the acceptor membrane, but the mechanisms remain poorly understood. We combined extensive molecular dynamics simulations...
2026-10-06 | MTBLS15933 | MetaboLights
GenomicsRegulation of cellular cholesterol distribution via non-vesicular lipid transport at ER-Golgi contact sites
Regulation of cellular cholesterol distribution via non-vesicular lipid transport at ER-Golgi contact sites
PRJNA1005938 | ENA
TranscriptomicsRegulation of cellular cholesterol distribution via non-vesicular lipid transport at ER-Golgi contact sites
Abnormal distribution of cellular cholesterol is associated with numerous diseases, including cardiovascular and neurodegenerative diseases. Regulated transport of cholesterol is critical for maintaining its proper distribution in the cell, yet the underlying mechanisms remain unclear. Here, we show...
ORGANISM(S): Homo sapiens 
2023-09-24 | GSE240960 | GEO
UnknownNon-Vesicular Lipid Transport Machinery in Leishmania donovani: Functional Implications in Host-Parasite Interaction.
Not available
S-EPMC10341546 | biostudies-literature
UnknownNon-vesicular sterol transport in cells.
Not available
S-EPMC2078525 | biostudies-literature
UnknownTricalbins Are Required for Non-vesicular Ceramide Transport at ER-Golgi Contacts and Modulate Lipid Droplet Biogenesis.
Not available
S-EPMC7648140 | biostudies-literature
UnknownS-palmitoylation modulates ATG2-dependent non-vesicular lipid transport during starvation-induced autophagy.
Not available
S-EPMC12048663 | biostudies-literature
UnknownGLTP mediated non-vesicular GM1 transport between native membranes.
Not available
S-EPMC3610762 | biostudies-literature
UnknownRegulation of cellular cholesterol distribution via non-vesicular lipid transport at ER-Golgi contact sites.
Not available
S-EPMC10514280 | biostudies-literature
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