Sort   by:  
 Page size 
ProteomicsDynamic monitoring of myeloma minimal residual disease with targeted mass spectrometry
Serum samples from multiple myeloma (MM) patients are collected regularly for conventional tests to quantify the M-protein longitudinally. However, the limited sensitivity of conventional tests makes quantification of minimal residual disease (MRD) difficult. MRD can be quantified with highly sensit...
ORGANISM(S): Homo Sapiens 
2023-02-27 | PXD038370 | panorama
ProteomicsRetrospective longitudinal monitoring of multiple myeloma patients by mass spectrometry using archived serum protein electrophoresis gels and de novo sequence analysis
M-proteins are antibody molecules produced by a clone of Multiple Myeloma cells. Thus, they are used as a disease activity marker. Traditionally, serum protein electrophoresis gels (SPEP) are used to quantify M-proteins. While effective for diagnostics, sensitivity of SPEP is limited. Here, we demon...
ORGANISM(S): Homo Sapiens 
2022-08-10 | PXD034406 | panorama
Sort   by:  
 Page size