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TranscriptomicsGenes enabling phenotypic plasticity evolve canalized gene expression by their limited associations with transcriptional regulators
Global climate change increasingly polarizes environments, presenting unprecedented challenges to many organisms (Smol, 2012). Polarization occurs not only in the spatial dimension, producing greater desert drought and tropical rainfall, for example, but also in the temporal dimension by making a lo...
ORGANISM(S): Fundulus heteroclitus 
2014-10-02 | E-GEOD-47035 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of 10 sample types: normal colon tissue, non cancerous adenomas, Dukes B carcinomas, Dukes C carcinomas, Dukes D carcinomas, and liver metastases, see also E-TIGR-14, E-TIGR-15
This study was designed to find patterns of gene expression in colon cancer samples that correlate with clinical stage. Ten samples were profiled from each of the following sample types: normal colon tissue, noncancerous adenomas, Dukes B carcinomas, Dukes C carcinomas, Dukes D carcinomas, and liver...
ORGANISM(S): Homo sapiens 
2005-01-01 | E-TIGR-14 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of human fetal lung and intestine tissue
Here, we performed single cell RNA sequencing (scRNA-seq) of 1 (one) human fetal lung tissue specimen (18.9 week) and 2 (two) human fetal intestine specimens (12.1 and 18.9 week) (total of 3 (three) independent biological specimens). The data set is composed of approximately 5,000 lung cells and 7,5...
ORGANISM(S): Homo sapiens 
2020-12-20 | E-MTAB-9363 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mice treated with varying concentrations of ovalbumin (see also E-TIGR-132 and E-TIGR-134)
For each strain, Ova-alum and alum-only sensitization is followed by ovalbumin challenge. Reactivity measured at 24, 48, 72 hrs for each group is compared to an ova-pre-control sample.
ORGANISM(S): Mus musculus 
2007-02-13 | E-TIGR-133 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mice treated with varying concentrations of ovalbumin (see also E-TIGR-132 and E-TIGR-133)
For each strain, Ova-alum and alum-only sensitization is followed by ovalbumin challenge. Reactivity measured at 24, 48, 72 hrs for each group is compared to an ova-pre-control sample.
ORGANISM(S): Mus musculus 
2007-02-12 | E-TIGR-134 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mice treated with varying concentrations of ovalbumin (see also E-TIGR-133 and E-TIGR-134)
For each strain, Ova-alum and alum-only sensitization is followed by ovalbumin challenge. Reactivity measured at 24, 48, 72 hrs for each group is compared to an ova-pre-control sample.
ORGANISM(S): Mus musculus 
2007-02-13 | E-TIGR-132 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of asthma induced mice treated with LPS in a controlled environment
Examination of gene expression associated with asthma induced by treatment of mice with LPS in a controlled environment, realted experiment E-TIGR-7.
ORGANISM(S): Mus musculus 
2005-01-01 | E-TIGR-8 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of asthma induced mice treated with LPS in a controlled environment
Examination of gene expression associated with asthma induced by treatment of mice with LPS in a controlled environment. Related experiment E-TIGR-8
ORGANISM(S): Mus musculus 
2005-01-01 | E-TIGR-7 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hypertension induced with chronic or acute angiotensin treatment in mouse, 2
Hypertension induced with chronic or acute angiotensin treatment in mouse. Related experiment E-TIGR-11
ORGANISM(S): Mus musculus 
2005-01-01 | E-TIGR-12 | biostudies-arrayexpress
TranscriptomicsHistone H3.3 and its proteolytically processed form drive a cellular senescence program
In this study, we have uncovered novel proteolytic processing of the histone H3 tail in senescence models in primary fibroblasts and melanocytes. Cleavage of H3 tail occurs at two distinct residues and is mediated by Cathepsin L. We show that variant H3.3 is preferentially cleaved, and that cleaved ...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-55949 | biostudies-arrayexpress
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