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TranscriptomicsImmune Responses to Pneumocystis Infection are Robust in Immunocompetent Mice but Absent in CD40 Ligand Deficient Mice
Pneumocystis is a pathogen of immunocompromised hosts but can also infect healthy hosts, in whom infection is rapidly controlled and cleared. To better understand the immune mechanisms contributing to clearance of infection, microarray methods were used to examine differential gene expression in the...
ORGANISM(S): Mus musculus 
2008-12-22 | E-GEOD-11005 | biostudies-arrayexpress
TranscriptomicsInflammatory response of trout head kidney to in vivo challenge with IHN virus and LPS
The response of the trout, O.mykiss, head kidney to bacterial lipopolysaccharide (LPS) or active and attenuated infectious hematopoietic necrosis virus (IHNV and attINHV respectively) intraperoniteal challenge, 24 and 72 hours post-injection, was investigated using a salmonid-specific cDNA microarra...
ORGANISM(S): Oncorhynchus mykiss 
2010-06-25 | E-GEOD-10272 | biostudies-arrayexpress
TranscriptomicsModulation of the immune response of turbot (Scophthalmus maximus) after infection with viral haemorragic septicaemia virus
Turbot (Scophthalmus maximus) is a valuable resource for aquaculture in Galicia (NW Spain). Since it has been observed that viral hemorraghic septicaemia can affect turbot, among other finfish, increase of knowledge in molecular factors affected by the exposure to pathogen could help to develop stra...
ORGANISM(S): Scophthalmus maximus 
2012-02-14 | E-GEOD-35804 | biostudies-arrayexpress
TranscriptomicsGene expression profile analysis of Manila clam (Ruditapes philippinarum) hemocytes after a Vibrio alginolyticus challenge using an immune-enriched oligo-microarray
The Manila clam (Ruditapes philippinarum) is a cultured bivalve species with high worldwide commercial importance. Nevertheless, diseases can cause high economical losses. For this reason, the study of immune genes in bivalve mollusks has increased in the last years. The present work describes the c...
ORGANISM(S): Ruditapes philippinarum 
2014-07-01 | E-GEOD-43274 | biostudies-arrayexpress
TranscriptomicsGene expression profile of hemocytes from Manila clam (Venerupis philippinarum) after a Perkinsus olseni challenge using an immune-enriched oligo-microarray
Parasites of the genus Perkinsus spp. cause high mortalities and economic losses to the most noticeable bivalves produced in the worldwide aquaculture. In this study, we analyze how P. olseni influences the gene expression profiles of hemocytes from Manila clam (Venerupis philippinarum) using experi...
ORGANISM(S): Ruditapes philippinarum 
2015-07-31 | E-GEOD-59399 | biostudies-arrayexpress
TranscriptomicsUse of an immune-specific microarray for identifying transcriptome profiles associated to VHSV infection or vaccination with a G gene- DNA vaccine in turbot (Scophthalmus maximus)
With the aim of shedding light on the protection conferred by the DNA vaccines based in the G glycoprotein of viral haemorrhagic septicaemia virus (VHSV) in turbot (Scophthalmus maximus) we have used a specific microarray highly enriched in antiviral sequences to carry out the transcriptomic study a...
ORGANISM(S): Scophthalmus maximus 
2015-04-01 | E-GEOD-56487 | biostudies-arrayexpress
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