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MetabolomicsNR-SAFE: a randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson's disease

Nicotinamide adenine dinucleotide (NAD) replenishment therapy using nicotinamide riboside (NR) shows promise for Parkinson’s disease (PD) and other neurodegenerative disorders. However, the optimal dose of NR remains unknown, and doses exceeding 2000 mg daily have not been tested in humans. To ev...

2025-04-09 | MTBLS8812 | MetaboLights
MetabolomicsNicotinamide Riboside is Uniquely Bioavailable in People and Mice
Nicotinamide riboside (NR) is in wide use as an NAD+ precursor vitamin. Here we conducted experiments to determine the time and dose-dependent effects of NR on blood, liver and heart NAD+ metabolism in people and mice. We report that human blood cell NAD+ can rise as much as 2.7-fold with a single d...
2016-09-09 | MTBLS368 | MetaboLights
GenomicsEscherichia coli P4-NR
Escherichia coli P4-NR Genome sequencing and assembly
PRJNA77697 | ENA
GenomicsEntomobrya nr. imitabilis
Entomobrya nr. imitabilis overview
PRJNA1416543 | ENA
GenomicsFrancisella tularensis strain:NR-28537
Complete Genome Sequence of the BEI Master Cell Bank Francisella tularensis LVS strain NR-28537
PRJNA668347 | ENA
GenomicsMassilia sp. NR 4-1 isolate:Bija 4-1 | cultivar:Myeong Nuri
Massilia sp. NR 4-1 isolate:Bija 4-1 | cultivar:Myeong Nuri Genome sequencing and assembly
PRJNA288534 | ENA
GenomicsCandidatus Schneideria nysicola strain:NR
Candidatus Schneideria nysicola strain:NR Genome sequencing and assembly
PRJNA723906 | ENA
GenomicsBacillus anthracis strain:NR-1041
Bacillus anthracis strain:NR-1041 Genome sequencing
PRJNA270580 | ENA
GenomicsCitrobacter portucalensis strain:NR-12
Citrobacter portucalensis strain:NR-12 Genome sequencing and assembly
PRJNA379205 | ENA
UnknownComprehensive assessment of NR ligand polypharmacology by a multiplex reporter NR assay.
Not available
S-EPMC8873415 | biostudies-literature
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