Nrf2-signaling - OmicsDI

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Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202 Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202. VA Roudebush Medical Center, Indianapolis, IN 46202 (1)
Director of Women’s Health Research Women’s Service Line Inova Health System Chief Scientific Officer Gynecologic Cancer Center of Excellence John P. Murtha Cancer Center Research Program Uniformed Services University of the Health Sciences (1)
Eastern Virginia Medical School Department of Microbiology and Molecular Cell Biology Leroy T. Canoles Jr. Cancer Research Center (1)
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Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, National Key Laboratory of Medical Molecular Biology & Department of Immunology, No 5 Dongdan Santiao, Dongcheng district, Beijing 100005, China (1)
National Yang-Ming University Proteomics Research Center,Taiwan (1)
Prof. Dr. Karolien De Bosscher - Staff Scientist VIB-UGent Center for Medical Biotechnology Albert Baertsoenkaai 3 - 9000 Gent - Belgium (1)
Professor, Human Biology, Fred Hutchinson Cancer Center, USA (1)
Qingdao University,China (1)
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University of Puerto Rico, Medical Sciences Campus, Translational Proteomics Center (1)
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Washington University School of Medicine Department of Cell Biology & Physiology Washington University in St. Louis (1)
Washington University in St Louis (1)

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Ellagic Acid Alleviates Colitis by Inhibiting Ferroptosis via Nrf2/GPX4 Signaling

Ferroptosis, an iron-dependent form of regulated cell death, has emerged as a key driver of intestinal epithelial injury in inflammatory bowel disease (IBD). The Nrf2–GPX4 signaling axis provides a critical defense against ferroptotic damage; however, its therapeutic modulation remains underexplo...

2025-12-19 | MTBLS13535 | MetaboLights

Transcription profiling of mouse Keap1-null (CKO) to investigate genetic and pharmacologic activation of Nrf2 signaling

Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct hepatic gene expression profiles between Keap1 knockout and triterpenoid treated mice; Loss of Nrf2 signaling increases susceptibility to acute toxicity, inflammation, and carcinogenesis in mice due to the inabilit...

ORGANISM(S): Mus musculus

2009-05-11 | E-GEOD-15633 | biostudies-arrayexpress

Heme-Nrf2 signaling shifts myeloid differentiation

PRJNA743340 | ENA

Characterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling

The activation of the transcription factor NF-E2-related factor 2 (Nrf2) maintains cellular homeostasis in response to oxidative stress by the regulation of multiple cytoprotective genes. Without stressors the activity of Nrf2 is inhibited by its interaction with the kelch-like ECH-associated protei...

ORGANISM(S): Mus musculus

2015-10-31 | E-GEOD-71695 | biostudies-arrayexpress

Pereira2020 - NRF2–p53 integrated-systems model of oxidative stress

Integrated-systems model of oxidative stress connecting NRF2 and p53 signaling pathways. Additional crosstalk linking oxidative stress to p53 inhibition, p53 to NRF2 through p21, and NRF2 to MDM2 was incorporated in this model. The NRF2 pathway was encoded as first- and second-order rate equations f...

2021-10-29 | MODEL2110270001 | BioModels

Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury

PRJNA1095826 | ENA

Not available

S-EPMC9739464 | biostudies-literature

Coxiella burnetii type IV secretion-mediated activation of host cell Nrf2 signaling

PRJNA1023926 | ENA

Keratinocyte-Macrophage Crosstalk by the Nrf2/Ccl2/EGF Signaling Axis Orchestrates Tissue Regeneration

PRJNA668615 | ENA

Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma

PRJNA682393 | ENA