Sort   by:  
 Page size 
ProteomicsSmall molecule interactome mapping by photo-affinity labeling (SIM-PAL)
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most common pharmaceutical agents in the world. However, despite well-studied interactions with cyclooxygenase-2, little is known about the broader proteomic interactions and additional mechanisms that the NSAIDs elicit. Here we present a...
ORGANISM(S): Homo sapiens (Human) 
2019-01-25 | PXD007094 | Pride
Photo-crosslinking Nsaid Proteome Interactome Binding site 
TranscriptomicsTranscription profiling of rat intestinal epithelial IEC-6 cells treated with non-steroidal anti-inflammatory agents to investigate gastrointestinal toxicity of NSAIDs
Non-steroidal anti-inflammatory drugs (NSAIDs) are used extensively as therapeutic agents, despite their well-documented gastrointestinal (GI) toxicity. Presently, the mechanisms responsible for NSAID-associated GI damage are incompletely understood. In this study, we used Microarray analysis to gen...
ORGANISM(S): Rattus norvegicus 
2009-03-27 | E-GEOD-7584 | biostudies-arrayexpress
TranscriptomicsNon-steroidal Anti-inflammatory Drugs Decrease E2F1 Expression and Inhibit Cell Growth in Ovarian Cancer Cells
Epidemiological studies have shown that the regular use of non-steroidal anti-inflammatory (NSAIDs) drugs is associated with a reduced risk of various cancers. In addition, in vitro and experiments in mouse models have demonstrated that NSAIDs decrease tumor initiation and/or progression of several ...
ORGANISM(S): Homo sapiens 
2014-06-20 | E-GEOD-45052 | biostudies-arrayexpress
GenomicNSAIDS and Somatic Mutations in Barrett's Esophagus

Background: Use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has been shown to protect against tetraploidy, aneuploidy, and chromosomal alterations in the metaplastic condition Barrett's esophagus (BE) and to lower the incidence and mortality of esophageal adenoc...

phs001654 | dbGaP
TranscriptomicsChange in gene expression of a canine melanoma cell line caused by exposure to nonsteroidal anti-inflammatory drugs (NSAIDs) .
Nonsteroidal anti-inflammatory drugs (NSAIDs) has been suggested as adjunctive anti-tumor agents in human and veterinary medicine. However, its anti-tumor molecular machinery is still controversial. Therefore, we performed whole transcriptome analysis to discover gene expression influenced by NSAIDs...
ORGANISM(S): Canis lupus familiaris 
2016-03-09 | E-GEOD-78988 | biostudies-arrayexpress
TranscriptomicsChange in gene expression of a canine melanoma cell line caused by exposure to nonsteroidal anti-inflammatory drugs (NSAIDs) .
Nonsteroidal anti-inflammatory drugs (NSAIDs) has been suggested as adjunctive anti-tumor agents in human and veterinary medicine. However, its anti-tumor molecular machinery is still controversial. Therefore, we performed whole transcriptome analysis to discover gene expression influenced by NSAIDs...
ORGANISM(S): Canis lupus familiaris 
2016-03-09 | GSE78988 | GEO
Genomics
Equine fecal microbiota sequencing in response to NSAIDs
PRJNA476368 | ENA
ClinicalDoes Omission of NSAIDs After Colorectal Cancer Operation Affect the Consumption of Opioids?
Patients undergoing an operation for colorectal cancer are normally treated with non-steroid-anti-inflammatory-drugs (NSAIDs) e.g. ibuprofen as pain medication after the operation. It is well known that NSAIDs can be harmful to kidney-and heart patients and some studies also have shown an increased ...
2343861 | ecrin-mdr-crc
TranscriptomicsPollutants bioavailability and toxicological risk from NSAIDs to marine mussels
Pharmaceutical compounds are emerging contaminants in aquatic environment due to their massive use (human and veterinary medicines, agriculture and aquaculture) and a limited removal by waste water treatment plants (WWTPs). In this work, a representative determination of ecotoxicological potential o...
ORGANISM(S): Mytilus galloprovincialis 
2016-02-22 | GSE66990 | GEO
UnknownNSAIDs affect dendritic cell cytokine production.
Not available
S-EPMC9560552 | biostudies-literature
Sort   by:  
 Page size