Nuclear localization signal

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UNIPROT ID/AC

O54910 (2)
Q60778 (2)
O88522 (2)
Q60680 (2)
O88351 (2)
P25799 (2)
Q9Z1E3 (2)
A0A1S3CTQ6_DIACI (1)
A0A1S3CU82_DIACI (1)
A0A1S3CUK5_DIACI (1)
A0A1S3CUN3_DIACI (1)
A0A1S3CUN9_DIACI (1)
A0A1S3CVR8_DIACI (1)
A0A1S3CVS6_DIACI (1)
A0A1S3CVX0_DIACI (1)
A0A1S3CW50_DIACI (1)
A0A1S3CWG9_DIACI (1)
A0A1S3CWH8_DIACI (1)
A0A1S3CWL5_DIACI (1)
A0A1S3CWM4_DIACI (1)
A0A1S3CWQ4_DIACI (1)
A0A1S3CWY8_DIACI (1)
A0A1S3CX64_DIACI (1)
A0A1S3CXA8_DIACI (1)
A0A1S3CXH2_DIACI (1)
A0A1S3CYI0_DIACI (1)
A0A1S3CYI8_DIACI (1)
A0A1S3CZ97_DIACI (1)
A0A1S3CZC3_DIACI (1)
A0A1S3CZG3_DIACI (1)

Metabolite Name

Baseline (1)
Standard mixture (1)
Methionin (1)
Histidine (1)
Leucine (1)
Cystine (1)
Arginine (1)
Lysine (1)
Tyrosine (1)
Threonine (1)
Proline (1)
Phenylalanine (1)
Isoleucine (1)
Glutamine (1)
Glucose (1)
Aspartic acid (1)

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fungi (1)
protozoa (1)

Modelling Approach

Ordinary differential equation model (5)

Modification

4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (302)
ChIP-seq (59)
ChIP-chip by tiling array (56)
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Other (10)
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Release Date

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1999 (14)
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1997 (6)

Lab affiliation

Head of the Curie Institute Mass Spectrometry Platform (3)
Dept. of Molecular Biosciences, University of Texas at Austin, Texas 78712 USA (2)
1-Tyrolean Cancer Research Institute (TKFI), Innrain 66, A-6020 Innsbruck, Austria 2-Institute of Molecular Biology and Center for Molecular Biosciences, University of Innsbruck, Technikerstrasse 25, A-6020 Innsbruck, Austria. (1)
1. Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom. 2. Department of Haematology, University of Cambridge, Cambridge, United Kingdom. 3.6. Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom. (1)
Aix Marseille Univ, CNRS, INSERM, Institut Paoli-Calmettes, CRCM, Marseille, France (1)
Ben May Department for Cancer Research, The University of Chicago, Chicago, IL, 60637, USA (1)
Biomedical Center, LMU Munich Molecular Biology Großhaderner Strasse 9 82152 Planegg-Martinsried Phone: (089) 2180 75420 (1)
Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen 2200, Denmark (1)
CRUK - Beatson Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (1)
CSIRO Biomedical Manufacturing Biology R&D Group (1)
CSIRO Biomedical Manufacturing Protein Mass Spectrometry Lab Parkville, VIC 3052, Australia (1)
Cellular Dynamics Laboratory, RIKEN Cluster for Pioneering Research (CPR),Saitama 3510198, Japan. Present address:Jikei University of Health Care Sciences, Graduate School of Medical Safety Management, Osaka, Japan. (1)
Center for Cancer Research, Massachusetts General Hospital, Boston MA, USA;Department of Chemistry and Chemical Biology, Harvard University, Cambridge MA, USA. (1)
Center for Genomic Regulation (CRG) University Pompeu Fabra (UPF) (1)
Chinese Academy of Sciences Shanghai Institute of Materia Medica (1)
Copenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark (1)
Dana-Farber Cancer Institute (1)
Department of Biology of the Cell Nucleus, Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, 142 20 Prague, Czech Republic (1)
Department of Biology, Center for RNA Biology, University of Rochester, Rochester, New York, United States of America (1)
Department of Cell Biology, Harvard Medical School, Boston, MA 02115 USA (1)
Department of Cell Biology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China (1)
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, SP 05508-000, BR (1)
Department of Chemistry, Department of Molecular Biosciences, and the Chemistry of Life Processes Institute, Northwestern University, Evanston, IL USA 60208 (1)
Department of Internal Medicine, Morsani College of Medicine, University of South Florida (1)
Department of Molecular Integrative Physiology University of Illinois at Urbana/Champaign Urbana, IL 61801 (1)
Department of Nuclear Medicine and Radiobiology Faculty of Medicine and Health Sciences Université de Sherbrooke Sherbrooke, Quebec, Canada (1)
Department of Proteomics and Signal Transduction, Systems Biology of Membrane Trafficking Research Group, Max-Planck Institute of Biochemistry, Martinsried, Germany (1)
Department of Proteomics, The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, DK-2200 Copenhagen, Denmark (1)
Director of the Institute Medizinisches Proteom-Center Gesundheitscampus 4 D-44801 Bochum Germnany (1)
EMBL, SCB, Heidelberg, Germany (1)

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Metabolomic profiling of cerebrospinal fluid from dogs with meningoencephalitis of unknown origin by nuclear magnetic resonance

Introduction: Meningoencephalitis of unknown origin (MUO) in dogs is a very debilitating and potentially fatal disease that is a potential model for multiple sclerosis in humans. The metabolomic profile of MUO has not been previously reported.

Objectives: To describe the metabolomic profile...

2026-03-05 | MTBLS6053 | MetaboLights

Knock-out of the nuclear localization in pp65 protein of Cytomegalovirus: biologic and immunologic effects

The CMVpp65 protein contains 2 bipartite nuclear localization signals (NLS) at 415-438aa and 537-561aa near the carboxy terminus of CMVpp65 and a phosphate binding site related to kinase activity at lysine-436. A mutation of pp65 having K436N (CMVpp65mII) and further deletion of aa537-561 resulted ...

ORGANISM(S): Homo sapiens

2009-01-30 | E-GEOD-14347 | biostudies-arrayexpress

TMT-based quantitative proteomics analysis reveals the attenuated replication mechanism of Newcastle disease virus caused by nuclear localization signal mutation in viral matrix protein

Nuclear localization of cytoplasmic RNA virus proteins mediated by intrinsic nuclear localization signal (NLS) plays essential roles in successful virus replication. We previously reported that NLS mutation in the matrix (M) protein obviously attenuates the replication and pathogenicity of Newcastle...

ORGANISM(S): Cricetidae

2020-05-22 | PXD018098 | Pride

Cytoplasmic Assembly and Selective Nuclear Import of Arabidopsis ARGONAUTE4/siRNA Complexes

Here we profiled small RNAs from whole cell, cytoplasmic and nuclear extracts from three-week-old Arabidopsis seedlings. We unexpectedly found that nuclear functional hc-siRNAs are predominantly present in the cytoplasm. Samples from Arabidopsis thaliana whole cell, cytoplasmic and nuclear extract...

ORGANISM(S): Arabidopsis thaliana

2012-07-12 | E-GEOD-36500 | biostudies-arrayexpress

WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import.

Not available

S-EPMC10942854 | biostudies-literature

Nuclear Localization of Hog1 MAPK is Not Necessary for Resistance to Hyperosmotic Stress

In budding yeast, this signaling pathway— the high-osmolarity glycerol (HOG) response —culminates in dual phosphorylation and nuclear translocation of the MAPK, Hog1 (ortholog of mammalian p38/SAPK). Induction of at least 50 genes requires nuclear Hog1, implying that transcriptional up-regulation...

ORGANISM(S): Saccharomyces cerevisiae

2008-06-01 | E-GEOD-8703 | biostudies-arrayexpress

Transcription profiling of cerebellum from transgenic mice with nuclear and extranuclear polyQ to investigate the role of polyQ in Huntingtons disease

To dissect the impact of nuclear and extranuclear mutant htt on the initiation and progression of disease, we generated a series of transgenic mouse lines in which nuclear localization (NLS) or nuclear export sequences (NES) have been placed N-terminal to the htt exon 1 protein carrying 144 glutamin...

ORGANISM(S): Mus musculus

2007-07-03 | E-GEOD-3248 | biostudies-arrayexpress

A C-terminal cytoplasmic retention motif and nuclear localization signal regulates nuclear import of TP53INP2.

Not available

S-EPMC12752491 | biostudies-literature

Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice

Huntington's disease (HD) is a dominantly inherited genetic disease caused by mutant huntingtin (htt) protein with expanded polyglutamine tracts. A neuropathological hallmark of HD is the presence of neuronal inclusions of mutant htt. p62 is an important regulatory protein in selective autophagy, ...

ORGANISM(S): Mus musculus

2014-10-10 | E-GEOD-62210 | biostudies-arrayexpress

Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.

Not available

S-EPMC3033682 | biostudies-literature

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