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TranscriptomicsLMP-420: a novel purine nucleoside analogue with potent cytotoxic effects for chronic lymphocytic leukemia cells
[original title] LMP-420: a novel purine nucleoside analogue with potent cytotoxic effects for chronic lymphocytic leukemia cells and minimal toxicity for normal hematopoietic cells. LMP-420 induces cytotoxicity and apoptosis to CLL cells in vitro without any negative effects to normal immune cells...
ORGANISM(S): Homo sapiens 
2011-02-01 | E-GEOD-20211 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human intestinal cells (Caco-2) and tissues from all intestinal segments (duodenum, jejunum, ileum, colon)
Affymetrix U95Av2 expression data from human intestinal cells (Caco-2) and tissues from all intestinal segments (duodenum, jejunum, ileum, colon). Entries contain the search terms glycosylase, phosphorylase, cytochrome or nucleoside, which were relevant to our search for enzymes capable of cleaving...
ORGANISM(S): Homo sapiens 
2007-06-21 | E-GEOD-1862 | biostudies-arrayexpress
TranscriptomicsLMP-420: a novel purine nucleoside analogue with potent cytotoxic effects for chronic lymphocytic leukemia cells
[original title] LMP-420: a novel purine nucleoside analogue with potent cytotoxic effects for chronic lymphocytic leukemia cells and minimal toxicity for normal hematopoietic cells. LMP-420 induces cytotoxicity and apoptosis to CLL cells in vitro without any negative effects to normal immune cells....
ORGANISM(S): Homo sapiens 
2011-02-01 | GSE20211 | GEO
ProteomicsDual protein kinase/ nucleoside kinase modulat ors for rationally designed polypharmacology
Masitinib, a highly selective protein kinase inhibitor, can sensitise gemcitabine-refractory cancer cell lines when used in combination with gemcitabine. A reverse proteomic approach has identified the target responsible for this sensitisation: the deoxycytidine kinase (dCK). Masitinib, as well as o...
ORGANISM(S): Homo sapiens (Human) 
2017-11-13 | PXD007765 | Pride
Human Ltq-velos-orbitrap Labelfree 
UnknownA diazirine-based nucleoside analogue for efficient DNA interstrand photocross-linking.
Not available
S-EPMC2945524 | biostudies-literature
UnknownDifferences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells.
Not available
S-EPMC8507139 | biostudies-literature
UnknownA ferrocene-containing nucleoside analogue targets DNA replication in pancreatic cancer cells.
Not available
S-EPMC9320222 | biostudies-literature
UnknownL-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase.
Not available
S-EPMC2531256 | biostudies-literature
UnknownRadiosynthesis of the anticancer nucleoside analogue Trifluridine using an automated 18F-trifluoromethylation procedure.
Not available
S-EPMC5944245 | biostudies-literature
UnknownNucleoside analogue 2'-C-methylcytidine inhibits hepatitis E virus replication but antagonizes ribavirin.
Not available
S-EPMC5602043 | biostudies-literature
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