Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of rat oxyntic mucoses after treatment with the Octreotide LAR
Previous studies have shown that treatment with the somatostatin analogue octreotide LAR causes regression of gastric ECL-cell carcinoids in patients with hypergastrinaemia due to chronic atrophic gastritis, reducing both the number and size of tumours. The main objective of the present study was to...
ORGANISM(S): Rattus norvegicus 
2008-06-14 | E-GEOD-5910 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis wild type, FIE- and MIA- loss-of-function mutants
Plants with genotypes wild type, FIE loss-of-function and MIA loss-of-function were compared. Plants were grown in growth chambers at 70% humidity and daily cycles of 16 h light and 8 h darkness at 21 C. Plant material used for the experiments was pooled from 10 plants. Siliques without withering fl...
ORGANISM(S): Arabidopsis thaliana 
2007-01-18 | E-ATMX-10 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of Arabidopsis 4 day-old light-treated seedlings using anti H3, CT, pan, anti H3K9me2 and IgG antibodies
ChIP was performed using 100 mg of 4 day-old light-treated seedlings. The following antibodies were used: anti H3, CT, pan (Millipore 07-690), anti H3K9me2 (Diagenode pAb-060-050) and IgG (Sigma I50006).
ORGANISM(S): Arabidopsis thaliana 
2009-12-08 | E-MEXP-2480 | biostudies-arrayexpress
TranscriptomicsChIP-chip by array of Arabidopsis endosperm nuclei expressing a PHE1::PHE1-GFP reporter using H3K27me3 and IgG antibodies
ChIP was performed using chromatin from sorted endosperm nuclei expressing a PHE1::PHE1-GFP reporter. The following antibodies were used: anti H3K27me3 (Millipore, cat. 07-449) and IgG (Sigma I50006).
ORGANISM(S): Arabidopsis thaliana 
2010-12-14 | E-TABM-1008 | biostudies-arrayexpress
Transcriptomicslar-Transcriptomic analysis of the localized acquired resistance (LAR) phenomenon in Arabidopsis thaliana
tri38-lar - lar - Analyse the transcriptome of Arabidopsis thaliana plants developing localized acquired resistance (LAR) and a hypersensitive response (HR). The goal is to identify genes inducing LAR and/or HR. Plants were treated either with PstDC3000 (avrRpm1)or MgCl2 (control plants). The sample...
ORGANISM(S): Arabidopsis thaliana 
2010-05-15 | E-GEOD-13390 | biostudies-arrayexpress
TranscriptomicsThe role of Hoxa9 and Meis1 in development of acute myeloid leukemia (mRNA)
OBJECTIVE: MEIS1, a HOX cofactor, collaborates with multiple HOX proteins, such as HOXA9, to accelerate the onset of acute myeloid leukemia (AML) through largely unknown molecular mechanisms. To further resolve these mechanisms, we conducted a structure-function analysis of Meis1 and gene expression...
ORGANISM(S): Mus musculus 
2016-09-01 | E-GEOD-75272 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human uveal melanoma cell lines 92-1, MP41 and UM22 treated with entinostat, JQ1 or DMSO
As part of the preclinical research for a recently published trial of combination therapy with the HDAC inhibitor entinostat and the PD1 inhibitor pembrolizumab, an experiment was performed to determined the influence of entinostat and the BET inhibitor JQ1 on the transcriptome of three uveal melano...
ORGANISM(S): Homo sapiens 
2021-09-09 | E-MTAB-11058 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of DeltaNp73 alpha expressing C2C12 myoblasts examined 6 and 24 hours after shifting the cells to a differentiation medium to study the functions of the individual members of P53 family.
The p53 family comprises the tumor suppressor p53 and the structural homologs p63 and p73. How the three family members cooperate in tumor suppression remains unclear. Here, we report different but complementary functions of the individual members for regulating retinoblastoma protein (RB) function ...
ORGANISM(S): Mus musculus 
2007-11-22 | E-GEOD-5447 | biostudies-arrayexpress
GenomicsActivation and repression by oncogenic Myc shapes tumour-specific gene expression profiles
In mammalian cells, the Myc oncoprotein binds to thousands of promoters. During mitogenic stimulation of primary lymphocytes, Myc promotes an increase in expression of virtually all genes. In contrast, Myc-driven tumour cells differ from normal cells in expression of specific sets of up- and downreg...
ORGANISM(S): Homo sapiens 
2014-07-10 | E-GEOD-44672 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis leaves and flowers labeled with three different kits and hybridized to AGRONOMICS1 arrays
RNA was labeled as technical replicates with three different kits and hybridized to AGRONOMICS1 arrays.
ORGANISM(S): Arabidopsis thaliana 
2010-03-02 | E-TABM-870 | biostudies-arrayexpress
Sort   by:  
 Page size