O'Rourke Brian B

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Division of Cardiology Johns Hopkins University School of Medicine Ross Research Building, Room 847 720 Rutland Avenue Baltimore, MD 21205 Phone: 410-614-0027 Email: dbrianfoster@jhmi.edu Web: http://web1.johnshopkins.edu/fosterlab (1)
Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 20205, USA (1)

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Circulating tumor cells and response to chemotherapy in metastatic breast cancer: SWOG S0500.

Not available

S-EPMC4209100 | biostudies-literature

Integrated Omic Analysis of a Guinea Pig Model of Heart Failure and Sudden Cardiac Death

Here we examine key regulatory pathways underlying the transition from compensated hypertrophy (HYP) to decompensated heart failure (HF) and sudden cardiac death (SCD) in a guinea pig model by integrated multi-ome analysis. Relative protein abundances from sham-operated, HYP and HF hearts were asses...

ORGANISM(S): Cavia porcellus (Guinea pig)

2018-10-26 | PXD003980 | Pride

Inhibition of Cardiac p38 Highlights the Role of the Phosphoproteome in Heart Failure Progression

We employed a guinea pig model of heart failure (HF) that combines ascending aortic constriction with daily administration of the β-adrenergic agonist isoproterenol (1 mg/kg/day for 1 hour) via an implanted programmable pump. The experimental groups included: 1) Sham-operated controls; 2) ACi (Aorti...

ORGANISM(S): Cavia porcellus (Guinea pig)

2025-09-08 | PXD058012 | Pride

Heart failure Guinea pig Heart P38 inhibition Tmt Lc-ms/ms

Identification and validation of gene expression changes upon removal of Dicer in the murine limb mesenchyme

Wild type and Dicer null embryonic mouse limbs were analaysed using Affymetrix arrays to identify gene expression changes. Genes that were up-regulated in Dicer-null limbs were canidates for being miRNA targets. Potential miRNA target genes were validated using qRTPCR. Mice carrying a heterozygous D...

ORGANISM(S): Mus musculus

2011-01-31 | E-GEOD-13807 | biostudies-arrayexpress

Calcium/vitamin D supplementation and coronary artery calcification in the Women's Health Initiative.