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ProteomicsNovel in vivo models of autosomal optic atrophy show conserved pathological changes in mitochondrial structure and function ZEBRAFISH DATASET
Autosomal optic atrophy (AOA) is a form of hereditary optic neuropathy characterized by the irreversible and progressive degermation of the retinal ganglion cells. Most cases of AOA are associated with a single dominant mutation in OPA1, which encodes a protein required for fusion of the inner mitoc...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-05-07 | PXD059584 | Pride
Zebrafish  drosophila  mitochondria  optic atrophy  visual impairment. project description: 
ProteomicsNovel in vivo models of autosomal optic atrophy show conserved pathological changes in mitochondrial structure and function Dataset 2 Drosophila
Autosomal optic atrophy (AOA) is a form of hereditary optic neuropathy characterized by the irreversible and progressive degermation of the retinal ganglion cells. Most cases of AOA are associated with a single dominant mutation in OPA1, which encodes a protein required for fusion of the inner mitoc...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-05-07 | PXD059645 | Pride
Zebrafish  drosophila  mitochondria  optic atrophy  visual impairment. 
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