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TranscriptomicsRNA Seq of control and Cyp26b1KO HSCs after 24h of in vitro culture and treatment
The transcriptome of Ctrl and Cyp26b1KO hematopoietic stem cells (HSC) after 24h in vitro culture upon retinoid treatment was assessed by RNAseq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-9752 | biostudies-arrayexpress
TranscriptomicsRNA Seq of wildtype and Rarb KO HSCs after 24h of in vitro culture and treatment
The transcriptome of WT and Rarb KO hematopoietic stem cells (HSC) after 24h in vitro culture upon retinoid treatment was assessed by RNAseq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-9749 | biostudies-arrayexpress
TranscriptomicsATAC-seq of control and Cyp26b1KO HSCs
The open chromatin of mouse control and Cyp26b1KO longterm hematopoietic stem cells has been profiled by ATAC-seq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-9778 | biostudies-arrayexpress
TranscriptomicsATAC-seq of HSCs in Vitamin A-free diet
The open chromatin of mouse longterm hematopoietic stem cells in control and vitamin A deficiency has been profiled by ATAC-seq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-9780 | biostudies-arrayexpress
TranscriptomicsATAC-seq of LT-HSCs and MPPs
The open chromatin of mouse longterm hematopoietic stem cells and multipotent progenitor cells has been profiled by ATAC-seq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-9779 | biostudies-arrayexpress
TranscriptomicsRNA Seq of 7-month old control and Cyp26b1KO LT-HSCs
The transcriptome of Ctrl and Cyp26b1KO longterm hematopoietic stem cells (LT-HSC) of 7-month old mice was assessed by RNAseq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-10659 | biostudies-arrayexpress
GenomicsChIPseq for H3K4me3 and H3K27me3 in LT-HSCs and MPPs
The distribution of H3K4- and H3K27me3 on the chromatin of mouse longterm hematopoietic stem cells and multipotent progenitor cells has been profiled by ChIP-seq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-10661 | biostudies-arrayexpress
TranscriptomicsRNA Seq of control and Cyp26b1 knockout mouse longterm hematopoietic stem cells
The transcriptome of Ctrl and Cyp26b1KO longterm hematopoietic stem cells (LT-HSC) was assessed by RNAseq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-9745 | biostudies-arrayexpress
TranscriptomicsPolycomb protein EED is required for selective silencing of pluripotency genes upon ESC differentiation
Eed (embryonic ectoderm development) is a core component of the Polycomb Repressive Complex 2 (PRC2) which catalyzes the methylation of histone H3 lysine 27 (H3K27). Trimethylated H3K27 (H3K27me3) can act as a signal for PRC1 recruitment in the process of gene silencing and chromatin condensation. P...
ORGANISM(S): Mus musculus 
2014-08-28 | E-GEOD-49305 | biostudies-arrayexpress
TranscriptomicsRNA Sequencing of LT-HSCs and ST-HSCs from healthy adult human Bone Marrow
The transcriptome of LT-HSC (CD34+CD38-CD45RA+CD90+CD49f+) and ST-HSC (CD34+CD38-CD45RA+CD90-CD49f-) from healthy adult human Bone Marrow Cells were assessed by RNA-seq.
ORGANISM(S): Homo sapiens 
2022-04-06 | E-MTAB-9892 | biostudies-arrayexpress
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